BACKGROUND Patient-reported outcomes (PRO) questionnaires are being increasingly used in COPD clinical studies. The challenge facing investigators is to determine what change is significant, ie what is the minimal clinically important difference (MCID). This study aimed to identify the MCID for the clinical COPD questionnaire (CCQ) in terms of patient referencing, criterion referencing, and by ...

log-odds; Medical Research Council, MRC; Shortness of Breath with Daily Activities questionnaire, SOBDA; excacerbation of chronic pulmonary disease tool, EXACT; forced expiratory volume in one second, FEV1 ; Chronic Respiratory Questionaire, CRQ; St. George’s Respiratory Questionaire, SGRQ; COPD Biomarker Qualification Consortium, CBQC; COPD Assessment Test, CAT; Clinical COPD Questionaire, CCQ...

OBJECTIVE To evaluate the effectiveness of a screening programme for COPD in primary care. MATERIAL/METHODS Subjects aged 65 years or older registered with a general practitioner in Copenhagen were asked to complete a questionnaire on smoking status and symptoms of COPD. If they were smokers or former smokers or if morning cough with sputum and/or dyspnoea was present, subjects were defined a...

BACKGROUND The Canadian Thoracic Society (CTS) has developed a clinical practice guideline (CPG) regarding the management of patients with chronic obstructive pulmonary disease (COPD). Implementation of this CPG in the primary care setting requires an effective dissemination strategy. OBJECTIVES To examine the change in knowledge, participant satisfaction and perceived changes in clinical pra...

Dr.Mirsadraei and colleagues performed an interesting study about the lung HRCT findings in chemical warfare patients who suffering from long-term pulmonary complications. They found that air trapping and mosaic attenuation were the most common lung HRCT findings. Also they divided patients in different clinical entities according to the lung HRCT findings (Bronchiolitis Oblitrans, pulmonary fi...

  Background: Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease, which reduces the lung function and causes respiratory symptoms over time, and it is primarily associated with shortness of breath, cough and sputum production. Roflumilast, which is a long-acting selective inhibitor, reduces the anti-inflammatory effect of the main symptoms of COPD. The aim of ...

BACKGROUND The development and validation study of the Clinical Chronic Obstructive Disease (COPD) Questionnaire (CCQ) has recently been published in this journal. The CCQ is the first questionnaire that incorporates both clinician and patient guideline goals in the clinical control evaluation of patients with COPD in general clinical practice. The aim of this study is the validation of the CCQ...

BACKGROUND Anxiety and depression are prevalent comorbidities in patients with COPD. Breathing techniques can improve anxiety and depression in patients hospitalized for COPD exacerbation. METHODS We conducted a randomized clinical study with 46 male subjects, 67-86 years old, hospitalized with acute COPD exacerbation. Subjects were randomly and equally divided into a control group and a cont...

BACKGROUND Clinical practice guidelines have been developed to assist healthcare practitioners in clinical decision making. Publication of clinical practice guidelines does not automatically lead to their uptake and barrier identification has been recognized as an important step in implementation planning. This study aimed at developing a questionnaire to identify perceived barriers for impleme...

BACKGROUND Little is known about the role of guidelines for the practical management of chronic obstructive pulmonary disease (COPD) by office-based pulmonary specialists. The aim of this study was to assess their outpatient management in relation to current guideline recommendations for COPD. METHODS A nationwide prospective cross-sectional COPD questionnaire survey in the form of a multiple...