نتایج جستجو برای: clone purification

تعداد نتایج: 94232  

2003
PETER OVE

Improved methods for growing animal cells in culture have led to their wide use as a tool in a variety of disciplines in biology. Cultures from many different anatomical origins are available and purification of several of them has been effected by the method of single clone isolation (1). The exact nature of the cultured cells and their relationship to the organ of their origin is, however, un...

2015
Yuan Gao

............................................................................................................................. ii Acknowledgements .......................................................................................................... iv List of Figures .................................................................................................................. vii List o...

Journal: :Journal of immunology 1983
R D Schreiber J L Pace S W Russell A Altman D H Katz

Biochemical and biosynthetic evidence has been obtained which indicates that the macrophage activating factor (MAF) produced by the murine T cell hybridoma clone 24/G1, which primes macrophages for nonspecific tumoricidal activity, is a form of gamma-interferon (IFN gamma). MAF and antiviral activities were generated by the clone in proportional amounts under a variety of culture conditions. Pr...

2013
Judith Scholz Hüseyin Besir Claudia Strasser Sabine Suppmann

BACKGROUND Expression and purification of correctly folded proteins typically require screening of different parameters such as protein variants, solubility enhancing tags or expression hosts. Parallel vector series that cover all variations are available, but not without compromise. We have established a fast, efficient and absolutely background free cloning approach that can be applied to any...

Journal: :Journal of virology 2004
F Guirakhoo Z Zhang G Myers B W Johnson K Pugachev R Nichols N Brown I Levenbook K Draper S Cyrek J Lang C Fournier B Barrere S Delagrave T P Monath

A chimeric yellow fever-dengue 1 (ChimeriVax-DEN1) virus was produced by the transfection of Vero cells with chimeric in vitro RNA transcripts. The cell culture supernatant was subjected to plaque purification for the identification of a vaccine candidate without mutations. Of 10 plaque-purified clones, 1 containing no mutation (clone J) was selected for production of the vaccine virus. During ...

2017
Hiroyuki Takeda Wei Zhou Kohki Kido Ryoji Suno Takahiro Iwasaki Takuya Kobayashi Tatsuya Sawasaki

There are many strategies to purify recombinant proteins of interest, and affinity purification utilizing monoclonal antibody that targets a linear epitope sequence is one of the essential techniques used in current biochemistry and structural biology. Here we introduce a new protein purification system using a very short CP5 tag. First, we selected anti-dopamine receptor D1 (DRD1) rabbit monoc...

Journal: :iranian journal of microbiology 0
esmat alemzadeh department of agricultural biotechnology, faculty of engineering and technology, imam khomeini international university, qazvin, iran. raheem haddad department of agricultural biotechnology, faculty of engineering and technology, imam khomeini international university, qazvin, iran. alireza ahmadi department of biomedical science, alzahra university, tehran, iran.

background and objectives: phytoplanktons are organisms with a very high diversities and global distribution in different habitats. the high distribution of phytoplankton is due to ecological flexibility and their ability to tolerate different climatic conditions and environmental stress. phytoplankton is the most sensitive biological indicators of water resources. the purpose of this study was...

Journal: :journal of paramedical sciences 0
amin daemi molecular immunology and vaccine research lab., pasteur institute of iran, tehran sahar hosseinzadeh islamic azad university of pharmaceutical science branch, tehran sima rafati molecular immunology and vaccine research lab., pasteur institute of iran, tehran farnaz zahedifard molecular immunology and vaccine research lab., pasteur institute of iran, tehran masoumeh rajabi bazl department of clinical biochemistry, shahid beheshti university of medical sciences fatemeh doustdari molecular immunology and vaccine research lab., pasteur institute of iran, tehran

the development of a therapeutic vaccine against human papillomavirus (hpv) is important for the control of cervical cancer. e7 is the major transforming protein produced in cervical cancers, and therefore represents potential tumor-specific antigen that could be the target of immunotherapy for cervical cancer. among different vaccine strategies, protein-based vaccines are capable of generating...

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