Previous work (Pearson, 1950; Pearson et al., 1952; and Visser et al., 1952) showed that various compounds may inhibit Theiler's GDVII strain of mouse encephalomyelitis virs in vitro; none tested so far was effective in vivo. It was of interest to determine if compounds capable of depressing centrl nervous stem activity would also repress virl activity. The present report gives the results of t...

The ethanol extract of Coccos nucifera (EECN) was tested for possible pharmacological effects on experimental animals. EECN significantly potentiated the sleeping time of mice induced by standard hypnotics viz. pentobarbital sodium, diazepam, and meprobamate in a dose dependent manner. EECN showed significant analgesic properties as evidenced by the significant reduction in the number of writhe...

Shade dried, powdered seeds of Sterculia guttata were extracted using a Soxhlet extractor with ethanol. Ethanol was removed under reduced pressure and dried to obtained crude extract. This extract was evaluated for its effect on behavioral changes, exploratory activity and barbiturate-sleeping time, using appropriate standard methods in mice. The extract exhibited dose-dependent CNS depressant ...

Background: Commelina diffusa Burm. (Family: Commelinaceae) is usually known as “climbing dayflower or spreading dayflower” in Bangladesh. The plant is used in fever, malaria, insect, bug bites, rheumatoid arthritis, gonorrhea, influenza, and bladder infection etc. The present investigation was undertaken which deals with the evaluation of central nervous system (CNS) depressant activity of met...

Gisekia Pharnaceoides Linn is a diffuse subsucculent, glabrous herb. It is aromatic, aperient and act as powerful anthelmintic in cases of taenia. The plant possesses antibacterial, CNS depressant and anthelmintic activity. The present communication deals with the morphology, anatomy, microscopic constants, Physicochemical constants preliminary phytochemical studies and fluorescence Linn.

29 29 GENERIC NAME PAGE Amphetamine 350 Caffeine 351 Doxapram 349 Fenfluramine 351 Methamphetamine 350 Methylphenidate 350 Modafenil 351 GENERIC NAME PAGE Pemoline 350 Pentylenetetrazol 349 Sibutramine 351 Phentermine 351 Theobromine 351 Theophylline 351 Central nervous system (CNS) stimulation is the primary action of a diverse group of pharmacological agents and an adverse effect associated w...

Ayurveda, Unani, Siddha and Homeopathy medicines are the major systems of indigenous medicines. Among these systems, Ayurveda is most trusted and widely practiced in India. Acorus calamus Roots and rhizomes have been used in Indian system of traditional medicine for hundreds of years and it is highly valued as a rejuvenator for the brain and nervous system and as a remedy for digestive disorder...

BACKGROUND Various parts of Pandanus foetidus Roxb. are used as traditional medicines. However, scientific reports concerning the effect of this plant on central nervous system (CNS) depression and analgesia are unavailable. This study investigated the CNS depressant and antinociceptive effects of Pandanus foetidus leaf extracts in a rodent model. METHODS The sedative and anxiolytic activitie...

Methanolic and ethyl acetate extract of A. galanga showed significant central nervous system (CNS) stimulant activity in mice using actophotometer and rotarod test. CNS stimulation at a dose of 500 mg/kg was comparable with standard drugs caffeine and amphetamine derivative modalart. The extracts did not shown any depressant effect in forced swim or tail suspension tests. It can be concluded th...