Idiopathic interstitial pneumonias include complex diseases that have a strong interaction between genetic makeup and environmental factors. However, in many cases, no infectious agent can be demonstrated, and these clinical diseases rapidly progress to death. Theoretically, idiopathic interstitial pneumonias could be caused by the Epstein-Barr virus, cytomegalovirus, adenovirus, hepatitis C vi...

Strong species specificity and similar tropisms suggest mouse cytomegalovirus (mCMV) as a potential vector for transgenes into human cells. We reexamined the dogma that mouse cytomegalovirus cannot productively replicate in human cells and found that mouse cytomegalovirus can produce infectious particles albeit at a level that does not sustain an infection. This finding demonstrates that mouse ...

1. Stagno S. Cytomegalovirus. In: Remington JS, Klein JO. Infectious diseases of the fetus and newborn. 4th ed. Philadelphia: WB Saunders, 1995: 312-53. 2. Bale JF, O'Neil ME, Fowler SS, Murph JR. Analysis of acquired human cytomegalovirus infections by polymerase chain reaction. J Clin Microbiol 1993;31:2433-8. 3. Studahl M, Ricksten A, Sandberg T, Bergstrom T. Cytomegalovirus encephalitis in ...

BACKGROUND & OBJECTIVES We undertook this study to determine the infectious aetiology of congenital cataract based on the presence of IgM antibodies to TORCHES [(Toxoplasma gondii (T. gondii), Rubella virus (RV), Cytomegalovirus (CMV), Herpes simplex virus (HSV) and Syphilis (caused by Treponema pallidum)] in the serum samples of congenital cataract patients. METHODS Serum samples collected f...

GOTHMAN, B. & OHLSSON, W.T.L. (1959) Fever with haematologic changes resembling infectious mononucleosis as a sequel of blood vessel grafting. Angiology, 10, 355. HAGER, E.B. & MERRILL, J.P. (1963) Peritoneal dialysis and acute renal failure. Surg. Clin. N. Amer. 43, 883. HORTON, E.H. (1966) Infectious mononucleosis-like syndrome after transfusion. Brit. med. J. i, 1419. KAARIANEN, L., KLEMOLA,...

In high-multiplicity infection of human fibroblasts, human cytomegalovirus of WI-38 human diploid cells produced early cell rounding 6 to 24 h after inoculation. This early cell rounding was caused only by inoculation with infectious virions. Inhibitors of protein synthesis, but not DNA inhibitors, prevented this cytopathic effect. Apparently, a new protein is synthesized in infected fibroblast...

GOTHMAN, B. & OHLSSON, W.T.L. (1959) Fever with haematologic changes resembling infectious mononucleosis as a sequel of blood vessel grafting. Angiology, 10, 355. HAGER, E.B. & MERRILL, J.P. (1963) Peritoneal dialysis and acute renal failure. Surg. Clin. N. Amer. 43, 883. HORTON, E.H. (1966) Infectious mononucleosis-like syndrome after transfusion. Brit. med. J. i, 1419. KAARIANEN, L., KLEMOLA,...

Immunoglobulin therapy has a rich history of use in preventing and treating infectious diseases; however, clinical data on the efficacy of immunoglobulin is lacking for many infectious diseases. Immunoglobulin therapy is routinely used in postexposure prophylaxis for bacterial infections, including tetanus, botulism, and diphtheria, and viral infections, including hepatitis A and B and varicell...

INTRODUCTION Infectious complications significantly increase morbidity and mortality after renal transplantation. The immunosuppression used is the main risk factor and relates directly to the incidence and severity of infectious events. METHODS This is a retrospective cohort study, which assessed the incidence of infections and their risk factors among 1,676 kidney transplant recipients duri...