in this report, magnetic iron oxide nanoparticles were synthesized via coprecipitation of fe2+ and fe3+ with ammonium hydroxide, and the surface of synthesized nanoparticles was organically functionalized by commercially available amine coupling agent namely, 3-aminopropyl trimethoxysilane (apts) by using well-known sol–gel method. further reaction of the synthesized fe3o4@apts core-shell magne...

we developed biofunctionalized nanoparticles with magnetic properties by immobalizing diethyle-neglycol (deg) on gd2o3, and pegilation of small particulate gadolinium oxide (spgo) with two me-thoxy-polyethyleneglycol-silane (mpeg-silane 550 and 2000 da) using a new supervised polyol route, described recently. in conjunction to the previous study to achieve a high quality synthesis and increase ...

SiO2-coated Cobalt Ferrite (CoFe2O4) nanoparticles were obtained by the hydrolysis of tetraethylorthosilicate in the presence of CoFe2O4 nanoparticles in co-precipitation. The effects of SiO2coating on the magnetic properties of CoFe2O4 nanoparticles were investigated. The structural, morphological and magne...

Thermoresponsive polymer-coated magnetic nanoparticles loaded with anti-cancer drugs are of considerable interest for novel multi-modal cancer therapies. Such nanoparticles can be used for magnetic drug targeting followed by simultaneous hyperthermia and drug release. Gamma-Fe(2)O(3) iron oxide magnetic nanoparticles (MNP) with average sizes of 14, 19 and 43 nm were synthesized by high temperat...

Magnetic nanoparticles for applications in separation and purification processes must satisfy several basic requirements. They should be superparamagnetic, i.e. possess low coercivity (H c ) and low retentivity (M r ), to enable re-dispersion after magnetic capture. In this study, the synthesis of SiO 2 coated γ-Fe 2 O 3 nanocomposite particles has been attempted to achieve the above magnetic p...

In magnetic particle assisted gene delivery DNA is complexed with polymer-coated aggregated magnetic nanoparticles (AMNPs) to effect transfection. In vitro studies based on COS-7 cells were carried out using pEGFP-N1 and pMIR-REPORT-complexed, polyethylenimine (PEI)-coated iron oxide magnetic nanoparticles (MNPs). PEI-coated AMNPs (PEI-AMNPs) with average individual particle diameters of 8, 16 ...

background: recently, applications of nanoparticles in many fields of medicine have been developed, due to their specific physical and chemical properties. therefore assessment of their toxicity specially in the in vivo condition is necessary. objectives: the aim of this study is to evaluation the effect of fe3o4 nanoparticles coating by biocompatible compounds on their toxicity and also compar...

When covalently bound to an appropriate ligand, iron oxide nanoparticles can bind to a specific target of interest. This interaction can be detected through changes in the solution's spin-spin relaxation times (T2) via magnetic relaxation measurements. In this report, a strategy of molecular mimicry was used in order to identify targeting ligands that bind to the cholera toxin B subunit (CTB). ...

a new hybrid nanomaterial was developed by immobilization of phosphomolybdate anions on the surface of modified magnetite nanoparticles with quaternary phosphonium cations. silica coated magnetic nanoparticles supported phosphonium cations, ph3p+-scmnps, were prepared by covalent attachment of chloropropylsilyl groups on the surface of silica coated magnetite nanoparticles and next reaction wit...

BACKGROUND Ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles are used as blood pool contrast agent for magnetic resonance angiography and perfusion imaging. Our aim in this study was to investigate the effect of the two coating types of iron oxide nanoparticles on the relationship between nanoparticles concentration and signal intensity (SI) in T1-weighted MR images. METHODS Diffe...