The variety of formats in which qualitative data may be collected have been explored within the methodological literature. Yet, multiple options for coding these not comprehensively detailed. While transcript analysis is widely used across disciplines, it limitations—particularly research involving marginalized populations. This paper presents a multimodal approach as innovation triangulating t...

Previously, we reported the presence in mouse cells of a mitochondrial RNA which contains an inverted repeat (IR) of 121 nucleotides (nt) covalently linked to the 5' end of the mitochondrial 16S RNA (16S mtrRNA). Here, we report the structure of an equivalent transcript of 2374 nt which is over-expressed in human proliferating cells but not in resting cells. The transcript contains a hairpin st...

The flowering plant Arabidopsis thaliana is a dicot model organism for research in many aspects of plant biology. A comprehensive annotation of its genome paves the way for understanding the functions and activities of all types of transcripts, including mRNA, the various classes of non-coding RNA, and small RNA. The TAIR10 annotation update had a profound impact on Arabidopsis research but was...

Background: Bladder cancer (BC) is the most commonly diagnosed genitourinary cancer in Iran, presented in both men and women. BC is a multifactorial trait resulting from the complex interaction between several genes and environmental factors. Long stress-induced non-coding transcript 5 (LSINCT5), a member of the long non-coding RNAs, is abundantly expressed in high proliferative cells, as well ...

We have identified gas5 (growth arrest-specific transcript 5) as a non-protein-coding multiple small nucleolar RNA (snoRNA) host gene similar to UHG (U22 host gene). Encoded within the 11 introns of the mouse gas5 gene are nine (10 in human) box C/D snoRNAs predicted to function in the 2'-O-methylation of rRNA. The only regions of conservation between mouse and human gas5 genes are their snoRNA...

Toward the identification of promoter structures in dicot plant mitochondria, transcription initiation sites were localized by in vitro capping of mitochondrial RNAs from Oenothera berteriana. By this approach at least 15 initiation sites are detectable in the genome. Primary 5'-transcript termini were determined for coxII, atpA, and an 18 S rRNA precursor. Alignment of the sequences surroundin...

A major determinant in the efficiency of ribosome loading onto mRNAs is the 5' TL (transcript leader or 5' UTR). In addition, elements within this region also impact on start site selection demonstrating that it can modulate the protein readout at both quantitative and qualitative levels. With the increasing wealth of data generated by the mining of the mammalian transcriptome, it has become ev...

We have characterized the 5' region of the rice actin 1 gene (Act1) and show that it is an efficient promoter for regulating the constitutive expression of a foreign gene in transgenic rice. By constructing plasmids with 5' regions from the rice Act1 gene fused to the coding sequence of a gene encoding bacterial beta-glucuronidase, we demonstrate that a region 1.3 kilobases upstream of the Act1...

Citation: Tian X, Ma J, Wang T, Tian J, Zhang Y, Mao L, Xu H and Wang S (2018) Long Non-Coding RNA HOXA Transcript Antisense RNA MyeloidSpecific 1–HOXA1 Axis Downregulates the Immunosuppressive Activity of Myeloid-Derived Suppressor Cells in Lung Cancer. Front. Immunol. 9:473. doi: 10.3389/fimmu.2018.00473 long non-coding rna hOXa Transcript antisense rna Myeloid-specific 1–hOXa1 axis Downregul...