OBJECTIVE A study was undertaken to determine whether better cognitive functioning at midlife among more physically fit individuals reflects neuroprotection, by which fitness protects against age-related cognitive decline, or neuroselection, by which children with higher cognitive functioning select more active lifestyles. METHODS Children in the Dunedin Longitudinal Study (N = 1,037) complet...

This study examines the relationship between cognitive functioning and depressive symptoms across 3 years in a prospective study of 273 community-dwelling, Hispanic older adults in Miami. The analyses extend the literature by testing for a bidirectional or reciprocal relationship between depressive symptoms and cognitive functioning over time and by examining the relationship between these vari...

Cognitive deficits predict functioning in schizophrenia; however, little is known as to whether the association is present in other mental disorders. If specific cognitive deficits uniquely predict functional impairment in schizophrenia the association of select aspects of brain dysfunction with daily living would suggest an intervention target and perhaps a means by which to improve the functi...

OBJECTIVES Several risk and protective factors are associated with changes in cognitive functioning in aging adults - including physical health, depression, physical activity, and social activities - though the findings for participation in social activities are mixed. This study investigated the longitudinal association between social participation and two domains of cognitive functioning, mem...

Wide bodies of literature document gradients in the experience of disease and function by levels of education and other measures of socioeconomic status: The lower a person’s education, the more likely the person will suffer from a greater variety and severity of diseases as well as functional disability arising from those diseases. It is unclear whether education proxies for other indicators o...

diabetes mellitus is associated with distribution of cognitive functioning. hyperglycemia diabetes mellitus is associated with distribution of cognitive functioning. hyperglycemia induced oxidative stress has been proposed as a cause of memory complications of diabetes including cognitive impairment. the aim of this study was to examine total green tea extract (tgte), a potent free radical scav...