background colorectal cancer (crc) is the second most common malignancy in the world.  however, its mortality rate can be reduced if diagnosed early. p33 ing1b is a tumor suppressor protein, which plays a role in growth control and apoptosis. suppression of p33 ing1b is associated with the loss of cellular growth control. however, p33 ing1b expression in crc and its correlations with clinicopat...

background: improvement in complications of antitumor agents and surgery is important to enhance life quality and survival among patients with colon and colorectal cancer. it has been reported that some dietary components such as glutamine (gln) have beneficial effects on these complications of cancer therapies. however, the results of studies are inconsistent in this area. we performed a revie...

aim : to investigate association between mthfr gene polymorphism with colorectal cancer. background : the enzyme 5,10-methylene-tetrahydrofolate reductase (mthfr) is linked to dna methylation, synthesis and repair. one of the most important polymorphisms that has been identified in the mthfr gene is c677t. the single nucleotide polymorphism c677t has been found to be associated with decreased e...

hypermethylation of cpg islands located in the promoter regions of genes is a major event in the development of the majority of cancer types, due to the subsequent aberrant silencing of important tumor suppressor genes. klotho; a novel gene associated primarily with suppressing senescence has been shown to contribute to tumorigenesis as a result of its impaired function. recently the relevance ...

Synchronous cancer is referred to two or more histological distinct malignancies diagnosed during the same hospital admission. Globally more than 1 million people get colorectal cancer yearly resulting in about 0.5 million deaths. Vulvar cancer is the fourth most common gynecologic cancer (following the corpus uterine cancer, cancer of ovary and cervix) and comprises only 4 percent of malignanc...

background : colorectal cancer is the most common cancer and the second leading cause of cancer deaths. annually it is the cause of more than 500000 deaths worldwide. therefore, detection and treatment of these tumors could potentially enhance recovery and improve prognosis. this study determines the frequency of colorectal tumors among patients who underwent colonoscopies in imam khomeini hosp...

colorectal cancer is an emerging public health problem in indonesia and currently ranks among the three highest cancers. lack of a colonoscopy screening and lifestyle changes might contribute to it. in the last few decades, there is an increasing interest towards the contribution of genetic-environment interaction in colorectal carcinogenesis. some studies have indicated that crc might develop ...

background: colorectal cancer (crc) is the third most common malignancy in iran. limited data are available on knowledge and barriers in regard to crc and screening tests in iran. the aim of  the study was to characterize knowledge, practice, and barriers toward crc and its screening tests among an iranian at‑risk population. methods: this cross‑sectional study was conducted with participation ...

background: today, cancer is one of the major health problems worldwide, and the importance of this disease in our country is growing. this cancer is the third cause of death and accounts for the second largest group of non-transmissible chronic diseases. colorectal cancer is the most common gastrointestinal cancer and includes 10%  of deaths from cancer around the world. different genetic and ...