4.1 Absorption, distribution, metabolism and excretion The disposition of various formulations of oral contraceptives used in humans differs. In general, both the oestrogenic and progestogenic compounds in combined oral contraceptives are absorbed by the gut and metabolized largely in the liver. A fraction of the absorbed dose of ethinyloestradiol and several progestogens is excreted in the bil...

Introduction Eighty per cent of contraceptive care occurs in the general practice setting. UK Medical Eligibility Criteria provides clear guidelines for the safe provision of appropriate contraception. The Faculty of Sexual and Reproductive Health and the National Institute for Health and Care Excellence offer further recommendations for initiation and continuation of the combined contraceptive...

STUDY OBJECTIVE To assess age specific incidence and mortality of stroke, acute myocardial infarction (AMI), and idiopathic venous thromboembolism (VTE) associated with use of modern low dose combined oral contraceptives (OCs) and the interaction with smoking. DESIGN Hospital-based case-control study. SETTING Hospitals in Oxford region in the United Kingdom, which covered a defined populati...

Combined oral contraception and treatment of new coronavirus infection (COVID-19): issues drug interaction This article examines the combined contraceptives with drugs recommended in (COVID-19) at pharmacodynamic pharmacokinetic levels, an assessment effectiveness safety therapy for female body.

introduction: the pilgrimage to ka’beh (god’s house in mecca) is a special opportunity in the life of most muslims. female pilgrims try to postpone menstruation during the pilgrimage by taking hormonal medicines. however, women are seen in this disorder. this paper aimed to determine the frequency of menstrual disorders and related factors among female pilgrims of umrah mufradah in 2012.methods...

AIMS To determine the extent of combined oral contraceptive use by girls aged 10-16 years in Scotland. METHODS Assessment of combined oral contraceptive prescribing in 35 414 girls for the year 1 November 1999-31 October 2000 from data retrieved from 161 primary care practices taking part in the Scottish Programme for Improving Clinical Effectiveness in Primary Care, and from national aggrega...

1. Nailfold capillary pressure, digital blood flow and skin temperature have been measured on days 7, 14, 21 and 28 of the menstrual cycle in 10 women on a combined oral contraceptive pill and 10 control subjects with normal menstrual cycles. 2. Capillary pressure and digital blood flow were statistically significantly higher in the group taking an oral contraceptive pill compared with control ...