Acute toxicity studies of crude extracts of resins of Commiphora myrrha, C. guidottii and C. erlangeriana, and pure compounds isolated from C. erlangeriana were conducted on Swiss albino mice. The extract from C. erlangeriana had a mean LD50 of 410 mg/kg body weight. However the extracts from C. myrrha and C. guidotti were not toxic at the doses tested. The pure compound isolated from C. erlang...

phytochemical screening, antioxidant and antibacterial activities of aqueous and methanolic crude extracts of commiphora kerstingii leaves were investigated. the antioxidant and antibacterial properties of different solvent extracts of commiphora kerstingii plant were scrutinized. the phytochemical screening of the various extracts was carried out using standard methods and the results revealed...

Background: Hyperandrogenism and insulin resistance are the main manifestations of polycystic ovary syndrome (PCOS), which appears to be caused by exposure to androgenized models have developed and investigated to study the etiology of polycystic ovary syndrome. Objective: To evaluate the modulatory effects of Commiphora wightii (C.wightii) resins in response to hyperandrogenism in polycystic o...

The biblical balm of Gilead (Commiphora gileadensis) was investigated in this study for anticancerous activity against tumor cell lines. The results obtained from ethanol-based extracts and from essential oils indicated that β-caryophyllene (trans-(1R,9S)-8-methylene-4,11,11-trimethylbicyclo[7.2.0]undec-4-ene) is a key component in essential oils extracted from the balm of Gilead. β-Caryophylle...

materials and methods thirty-two adult male wistar rats were randomly allocated to four groups: normal, diabetic, normal + extract of c. mukul and diabetic + extract of c. mukul groups with free access to regular rat diet. diabetes was induced in male rats by single interaperitoneal injection of 60 mg/kg stz. after the confirmation of diabetes, 300 mg/kg c. mukul extract was orally administered...

Oleo-gum resins such as frankincense and myrrh are some of the economically and culturally valuable products obtained from trees and shrubs of the genera Boswellia and Commiphora, respectively. They are important natural plant products used in several industries that include pharmacology, food, flavour, liqueur and beverage, cosmetics, perfumery and others. Moreover, frankincense and myrrh have...

Commiphora species are of high medicinal importance. They distributed in Saudi Arabia, mainly rocky habitats and regions under mountains, including the east Tihama, forming a distinct element flora. The present study focuses on botanical characterization five Commiphora, i.e., C. erythraea, gileadensis, kataf, myrrha, quadricincta. morphological characters for each were recorded comparatively, ...

The results of this study indicate that melatonin induces hypothyroidism in mice within eight days. Simultaneous administration of melatonin and petroleum ether extract of Commiphora mukul brings about a significant improvement in thyroid structure and function. Further, melatonin induced hypothyroidism is although a little reversible yet it is normalized quickly after C. mukul treatment. These...