The vast majority of genome-wide association study (GWAS) findings reported to date are from populations with European Ancestry (EA), and it is not yet clear how broadly the genetic associations described will generalize to populations of diverse ancestry. The Population Architecture Using Genomics and Epidemiology (PAGE) study is a consortium of multi-ancestry, population-based studies formed ...

Emergence Agitation (EA) is a common postoperative problem especially in children. It is more common in paediatric age group especially with low blood gas solubility inhalational agents like Sevoflurane and Desflurane. Other factors contributing to increase EA are head and neck surgeries, preoperative anxiety and pain. It increases the risk of postoperative physical trauma to patient like surgi...

In recent years, enterprise architecture (EA) management has emerged to one of the major challenges for enterprises. When looking for guidance in this field companies can choose from a variety of EA management approaches, which have been developed by scientists, practitioners, and governmental organizations. However, these approaches differ significantly in a number of characteristics and espec...

This paper describes a memory enhanced evolutionary algorithm (EA) approach to the dynamic job shop scheduling problem. Memory enhanced EAs have been widely investigated for other dynamic optimization problems with changing fitness landscapes, but only when associated with a fixed search space. In dynamic scheduling, the search space shifts as jobs are completed and new jobs arrive, so memory e...

BACKGROUND Emergence agitation (EA) in children after sevoflurane anesthesia is common. The purpose of this study was to compare the incidences of EA between ketamine and thiopental sodium induction in children underwent sevoflurane anesthesia. We also evaluated if a small dose of fentanyl could reduce the incidence of EA. METHODS The patients who were scheduled for strabismus or entropion su...

Objective(s): Cerebral ischemia/reperfusion (I/R) causes brain inflammation that ultimately causes long time brain function disturbances. We aimed to evaluate the effect of ellagic acid (EA) on anxiety, depression, locomotion behaviors, blood-brain barrier (BBB) permeability, brain edema, and inflammation in male rats with cerebral I/R. Materials and ...

Randia dumetorum (RD) fruits in different form have been ethnopharmacologically reported to possess antiasthmatic property. Therefore, present study was undertaken to evaluate two different extracts of RD i.e., ethyl acetate (RD-EA) and methanol (RD-ME) for bronchorelaxant, anti-inflammatory, mast cell stabilizing and antioxidant effect along with safety margin, according to OECD guidelines for...

BACKGROUND Several cancer-associated loci identified from genome-wide association studies (GWAS) have been associated with risks of multiple cancer sites, suggesting pleiotropic effects. We investigated whether GWAS-identified risk variants for other common cancers are associated with risk of esophageal adenocarcinoma (EA) or its precursor, Barrett's esophagus. METHODS We examined the associa...