AIM To precisely quantify the circumferential strains created along the radicular dentin of maxillary incisors during a simulated clinical procedure of lateral compaction. METHODS Six miniature strain gauges were bonded on the roots of fourteen recently extracted maxillary central incisors that were subjected to root canal instrumentation. The strain gauges were bonded at three levels (apical...

Dry granulation using roll compaction is a typical unit operation for producing solid dosage forms in the pharmaceutical industry. Dry granulation is commonly used if the powder mixture is sensitive to heat and moisture and has poor flow properties. The output of roll compaction is compacted ribbons that exhibit different properties based on the adjusted process parameters. These ribbons are th...

Current models used in our laboratory to assess the migration and traction of a population of cells within biopolymer gels are extended to investigate temporal changes in these parameters during compaction of mechanically constrained gels. The random cell migration coefficient, micro (t) is calculated using a windowing technique by regressing the mean-squared displacement of cells tracked at hi...

The bacterial chromosomal DNA is folded into a compact structure called as 'nucleoid' so that the bacterial genome can be accommodated inside the cell. The shape and size of the nucleoid are determined by several factors including DNA supercoiling, macromolecular crowding and nucleoid associated proteins (NAPs). NAPs bind to different sites of the genome in sequence specific or non-sequence spe...

HU is one of the most abundant proteins in bacterial chromosomes and participates in nucleoid compaction and gene regulation. We report experiments using DNA stretching that study the dependence of DNA condensation by HU on force, salt and HU concentration. Previous experiments at sub-physiological salt levels revealed that low concentrations of HU could compact DNA, whereas larger HU concentra...

Cardiomyopathies due to mutations in human β-cardiac myosin are a significant cause of heart failure, sudden death, and arrhythmia. To understand the underlying molecular basis of changes in the contractile system's force production due to such mutations and search for potential drugs that restore force generation, an in vitro assay is necessary to evaluate cardiac myosin's ensemble force using...

soil compaction is an important aspect of agriculture and different methods are available to measure this parameter. one method is called the cone index; measuring the force required per unit area for penetration of a standard steel cone into the ground. cone penetrometers are used for cone index measurement. in this study, a tractor mounted, hydraulically-operated penetrometer was designed, bu...

In order to provide a new method study the migration behavior of coarse aggregates in compaction process asphalt mixtures, “Intelligent Aggregate Attitude Acquisition System (IAS)” is developed based on 3D printing technology and wireless intelligent sensing technology, (IAA)” prepared as acquisition terminal. The Superpave Gyratory Compaction (SGC) test Internet Things (IOT) sensor are combine...