BACKGROUND AND PURPOSE We verified the propriety of our systematic error reduction strategy by means of a computer simulation based on our data of position error with a prone fixation device for prostate IMRT. MATERIALS AND METHODS Computer simulations of the off-line correction method for systematic setup errors based on the portal imaging taken on the first several days of the treatment ses...

A methodology for the dosimetric verification of micro-multileaf collimator MMLC) based intensity modulated radiation therapy (IMRT) plans intended for stereotactic applications is described. The procedure is similar to that of conventional IMRT patient-specific quality assurance with some notable exceptions. Relative dosimetry measurements are performed with radiographic film, a commercial fil...

PURPOSE To determine the patterns of failure after intensity-modulated radiation therapy (IMRT) for localized intracranial ependymoma. METHODS AND MATERIALS From 1994 to 2005, 22 children with pathologically proven, localized, intracranial ependymoma were treated with adjuvant IMRT. Of the patients, 12 (55%) had an infratentorial tumor and 14 (64%) had anaplastic histology. Five patients had ...

June 01, 2008 External-beam radiation is a highly effective curative treatment option for men with localized prostate cancer.[1,2] Over the past several decades, efforts have been made to improve the “therapeutic ratio” of radiation by increasing dose to improve cure rates without causing a substantial increase in side effects. Due to its potential to create superior dose distributions, proton ...

The contemporary treatment of anal cancer is combined-modality therapy with radiation therapy, fluorouracil, and mitomycin. This therapy results in long-term disease-free survival and sphincter preservation in the majority of patients. Tempering these positive results is the high rate of treatment-related morbidity associated with chemoradiation therapy for anal cancer. The use of intensity-mod...

BACKGROUND An advantage of the Intensity Modulated Radiotherapy (IMRT) technique is the feasibility to deliver different therapeutic dose levels to PTVs in a single treatment session using the Simultaneous Integrated Boost (SIB) technique. The paper aims to describe an automated tool to calculate the dose to be delivered with the SIB-IMRT technique in different anatomical regions that have the ...