background: serum prolactin level has been used as an alternative determinant to help differentiate epileptic from non-epileptic seizures. we aimed to analyze the association between serum prolactin concentration and epileptic seizure versus febrile seizure as well as seizure duration, single versus multiple seizure attacks and time lapse between seizure onset and blood sampling.   methods: sev...

Sixty cases of febrile seizures from a Chinese cohort had previously been reported with a strong association between variants in the seizure-related (SEZ) 6 gene and febrile seizures. They found a striking lack of genetic variation in their controls. We found genetic variation in SEZ6 at similar levels at the same DNA sequence positions in our 94 febrile seizure cases as in our 96 unaffected co...

objective simple febrile seizures are the most common form of childhood seizures,often recurring within the first twenty-four hours. this study was conducted to determine the probable role of low serum  sodium levels in predicting seizure recurrence in febrile children. materials & methods for the study, 226 patients with seizures, aged between 6 months to 5 years, were divided into 3 groups of...

430 www.thelancet.com Vol 372 August 9, 2008 in the general population, it is diffi cult to exclude chance as an explanation for their fi ndings. In today’s study, Vestergaard and colleagues tested the hypothesis that febrile seizures are associated with an increased risk of death, by examining mortality data from a cohort of more than 1·6 million children, including over 55 000 children with f...

BACKGROUND Since clinical signs of meningeal irritation in infants may be absent or misleading, the American Academy of Pediatrics in 1996 recommended that a lumbar puncture be performed in young children following a febrile seizure. Recent evidence supports a conservative approach in children who do not look ill at the time of the physician's assessment. Moreover, seizures as the presenting or...

A child with a febrile seizure is a common cause of admission in a general paediatric ward in Malaysia. We set out to look prospectively into the clinical and epidemiological features of these children. A total of 117 children were admitted into the study. The ratio of boys to girls were 1.5:1.0. The racial breakdown was 62.4% Malays, 26.5% Indians, 8.5% Chinese and 2.6% others. The first febri...

The aim of this study is to investigate the associations between febrile seizure and serum levels of vitamin B12, folic acid, and homocysteine. One hundred and four children who presented with febrile seizure and 75 controls who presented with febrile illness unaccompanied by seizure were enrolled into the study. Mean levels of vitamin B12, folic acid and homocysteine were compared between two ...