iodine is essential element in thyroid hormones synthesis and normal growth and development of the brain. milk and iodine concentrations can be appropriate indicator of body iodine status; in this study, we evaluated the concentrations of urine and milk iodine in newborns and their mothers.in a cross-sectional study conducted in 2013, urine and milk iodine in 106 neonates and their mothers refe...

BACKGROUND Thyroid hormone treatment in children with congenital hypothyroidism can prevent intellectual disability. Guidelines recommend that children diagnosed with congenital hypothyroidism through newborn screening remain on treatment to at least 3 years of age, after which a trial off therapy can determine which children have transient hypothyroidism. The purpose of this study was to descr...

background: several studies have demonstrated an increased risk of congenital hypothyroidism (ch) in girls in comparison to boys. objectives: the aim of this study was to determine the potential interactions that are able to change the effect of gender on congenital hypothyroidism. patients and methods: we conducted a matched 1:4 case-control study in hamadan province, western of iran, from 200...

OBJECTIVE To evaluate thyroid function in children with Down's syndrome, and to ascertain the presence of a relationship between overt thyroid diseases and congenital anomalies. MATERIAL AND METHOD One hundred and forty Down's syndrome patients, aged from 3 days to 13 years 9 months, were evaluated for karyotype, thyroid functions and the coexistence of congenital anomalies. RESULTS Trisomy...

Congenital hypothyroidism is the most frequent congenital endocrine disorder and prevent‐ able cause of mental retardation. The remarkable irreversible mental damage can be avoided by the replacement therapy introduced before the age of 3 weeks. Therefore a screening program implemented in the early seventies to pick up the affected babies on the first weeks of life [1,2]. After pilot studies s...

background: the aim of this study was to investigate the relationship between congenital hypothyroidism and several variables using two different adjustment methods. methods: this matched case-control study was conducted in hamadan province, the west of iran, in 2012 enrolling neonates born between 2005 and 2011 and covered by screening program for congenital hypothyroidism. the neonates with t...

Introduction: Congenital hypothyroidism is a preventable cause of intellectual disability in childhood. It one the commonest endocrine conditions encountered neonatal period. Maternal Thyroid Status has long been recognized as having an impact on developing fetus, and more recently family history thyroid dysfunction implicated risk factor congenital (CH). Therefore, this study focused screening...