Antibody affinity is an important determinant of all antibody-antigen reactions. A new computer program, AFCRV, was developed to calculate binding constants with data from a radioimmunoassay on most microcomputers in the laboratory by using constant-ratio dilution curves. Evaluation of a homogeneous or heterogeneous antibody in the presence of a single antigen can be accomplished.

The aim was to investigate the correlation between estimates of compression ratio, compression threshold, and cochlear gain for normal-hearing subjects inferred from temporal masking curves (TMC) and distortion-product otoacoustic emission (DPOAEs) input-output (I/O) curves. Special care was given to reduce the influence of DPOAE fine structure on the I/O curves. Data were collected for 10 subj...