نتایج جستجو برای: coprecipitation magnetic properties hyperthermia

تعداد نتایج: 1177551  

Journal: :Acta biomaterialia 2010
S Purushotham R V Ramanujan

The synthesis, characterization and property evaluation of drug-loaded polymer-coated magnetic nanoparticles (MNPs) relevant to multimodal cancer therapy has been studied. The hyperthermia and controlled drug release characteristics of these particles was examined. Magnetite (Fe(3)O(4))-poly-n-(isopropylacrylamide) (PNIPAM) composite MNPs were synthesized in a core-shell morphology by dispersio...

Journal: :Proceedings of the National Aviation University 2019

2012
Daozhen Chen Qiusha Tang Xiangdong Li Xiaojin Zhou Jia Zang Wen-qun Xue Jing-ying Xiang Cai-qin Guo

BACKGROUND The objective of this study was to evaluate the synthesis and biocompatibility of Fe₃O₄ nanoparticles and investigate their therapeutic effects when combined with magnetic fluid hyperthermia on cultured MCF-7 cancer cells. METHODS Magnetic Fe₃O₄ nanoparticles were prepared using a coprecipitation method. The appearance, structure, phase composition, functional groups, surface charg...

2013
JIAYI LIU NING LI LI LI DANYE LI KAI LIU LINGYUN ZHAO JINTIAN TANG LIYA LI

Magnetic-mediated hyperthermia (MMH) is a promising local thermotherapy approach for cancer treatment. The present study investigated the feasibility and effectiveness of MMH in esophageal cancer using a rabbit tumor model. The therapeutic effect of two hyperthermia approaches, magnetic stent hyperthermia (MSH), in which heat is induced by the clinical stent that is placed inside the esophagus,...

2015
Rui Yang Qiusha Tang Fengqin Miao Yanli An Mengfei Li Yong Han Xihui Wang Juan Wang Peidang Liu Rong Chen

PURPOSE To explore the thermoresistance and expression of heat-shock protein 90 (HSP90) in magnetic hyperthermia-treated human liver cancer stem-like cells (LCSCs) and the effects of a heat-shock protein HSP90 inhibitor 17-allylamino-17-demethoxgeldanamycin (17-AAG) on hepatocellular carcinoma-burdened nude mice. METHODS CD90(+) LCSCs were isolated by magnetic-activated cell sorting from BEL-...

2004
Martin A. M. Gijs

This review describes recent advances in the handling and manipulation of magnetic particles in microfluidic systems. Starting from the properties of magnetic nanoparticles and microparticles, their use in magnetic separation, immuno-assays, magnetic resonance imaging, drug delivery, and hyperthermia is discussed. We then focus on new developments in magnetic manipulation, separation, transport...

2013
Merlis P Alvarez-Berríos Amalchi Castillo Janet Mendéz Orlando Soto Carlos Rinaldi Madeline Torres-Lugo

Magnetic fluid hyperthermia as a cancer treatment method is an attractive alternative to other forms of hyperthermia. It is based on the heat released by magnetic nanoparticles subjected to an alternating magnetic field. Recent studies have shown that magnetic fluid hyperthermia-treated cells respond significantly better to chemotherapeutic treatment compared with cells treated with hot water h...

2009
Fuping Gao Yuanyuan Cai Jing Zhou Xiaoxue Xie Weiwei Ouyang Yuhui Zhang Xufei Wang Xiaodong Zhang Xiaowen Wang Lingyun Zhao Jintian Tang

Amphipathic polymer pullulan acetate (PA)-coated magnetic nanoparticles were prepared and characterized by various physicochemical means. The cytotoxicity and cellular uptake of the magnetic nanoparticles were examined. The hyperthermic effect of the magnetic nanoparticles on tumor cells was evaluated. Transmission electron microscopy (TEM) showed that the PA coated magnetic nanoparticles (PAMN...

2013
Carlos Martinez-Boubeta Konstantinos Simeonidis Antonios Makridis Makis Angelakeris Oscar Iglesias Pablo Guardia Andreu Cabot Lluis Yedra Sonia Estradé Francesca Peiró Zineb Saghi Paul A. Midgley Iván Conde-Leborán David Serantes Daniel Baldomir

The performance of magnetic nanoparticles is intimately entwined with their structure, mean size and magnetic anisotropy. Besides, ensembles offer a unique way of engineering the magnetic response by modifying the strength of the dipolar interactions between particles. Here we report on an experimental and theoretical analysis of magnetic hyperthermia, a rapidly developing technique in medical ...

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