Purpose: To describe a rare bilateral corneal ringshaped opacity, not categorized as corneal dystrophy or degeneration occurring without any associated ocular or systemic disease. Methods: Case report and review of the literature. Results: The authors describe the clinical history and examination of an 80 years old man, with an asymptomatic bilateral and symmetrical ring-shaped corneal opacity ...

Brian S. Boxer Wachler, MD The significant findings are lamellar channel deposits and superior neovascularization. The former are benign; they do not affect corneal health but can cause cosmetic concerns. Lamellar channel deposits can sometimes cause glare if the ring segment is located close to the pupil or if the pupil is large. These deposits are more likely to occur in wide versus narrow ch...

PURPOSE Excimer laser photorefractive keratectomy creates a nonvascular wound of the cornea. Fibrin deposition and resolution after excimer laser photokeratectomy were investigated in relation to corneal repair and restoration of clarity in mice with a genetic deficiency of plasminogen. METHODS A Summit Apex Laser (Summit, Waltham, MA) was used to perform 2-mm, 175-pulse, transepithelial phot...

Several methods of producing calcification of the cornea in experimental animals are presented. Experimental corneal calcification resulted from a combination of treatment with dihydrotachysterol (DHT) and corneal injury. In rabbits, six varieties of corneal injuries were inflicted: de-epithelization of the entire or central part of the cornea, abrasion of the central posterior surface, a combi...

PURPOSE To observe the clinical and histopathological changes occurring in corneas of KKAy mice, a model of type 2 diabetes, and to elucidate the possible mechanisms involved in these changes. METHODS Corneal epithelial cell proliferation was analyzed in KKAy and age-matched non-diabetic C57BL/6J control mice using (3)H-thymidine autoradiography. Clinical examination and histopathological ana...

CASE REPORT A 60-year-old woman with rheumatoid arthritis of 20 years onset, on treatment with monthly intramuscular gold salts (GS) for the last 7 years. She complained of suffering from halo vision, and the examination showed a visual acuity of 0.6 in both eyes (BE). The slit lamp showed some deposits in the stroma with scattered golden granulated, without any further inflammatory reaction. ...

In 1937 Bietti reported a tapetoretinal degeneration with associated corneal deposits at the limbus. The hallmark of the disease was the crystalline characteristics of the retinal spots as well as those at the corneal limbus. Bagolini and Ioli-Spade in 1968 presented a 30 year follow-up on Bietti's cases and presented six additional cases. The present report delas with this entity in Orientals,...

An interest in the possibility of a systemic lipid disturbance in Schnyder's corneal dystrophy stems from the work of Bonnet, Paufique, and Bonamour (I934), who first suggested that the needle-shaped corneal deposits in this condition consisted of cholesterol. The present study is of great interest since it describes a family in which Schnyder's central crystalline stromal dystrophy coexisted w...

Histochemical evidence suggests that the amorphous stromal deposits of corneal granular dystrophy are composed essentially of a non-collagenous protein or polypeptide complex, the precise nature of which, however, is unknown (Seitz and Goslar, I963; Garner, I969). Electron microscopy fortunately enables a further dimension of this material to be studied, and the present report gives the finding...

[1] Fluvial deposits in a basin north of Holden crater exhibiting a sinuous, anabranching pattern are of deltaic or fan origin. Channel width and meander wavelength indicate persistent flow magnitudes of about 700 m/s. If these flows were produced by quasi-periodic climate episodes involving typical terrestrial-style precipitation, the deposit required thousands to millions of years to accumula...