BACKGROUND The baseline data pertaining to the national epidemiological survey of infectious keratitis remain scarce in China, and currently there is no corneal blindness control strategy developed by the nation. METHODS Geographically defined cluster sampling was used to randomly select a cross-section of residents from representative urban and rural populations in Hubei Province. Participan...

OBJECTIVES To describe a microsurgical approach to a selective pedunculated conjunctival flap for the treatment of chronic corneal ulceration with or without corneal perforation, and to present the results of 50 consecutive cases. DESIGN Retrospective, noncomparative case series and case reports. Patients All patients who had microsurgical conjunctival flap procedures for the treatment of chr...

Sloughing virulent corneal ulcers are still very common in India. Even with the best medication they often fail to respond and in such cases the eyes are invariably lost. This is especially true in the case of ulcers caused by Pseudomonas pyocyaneus, when the clinical course is so fulminating that only a bold and timely decision can save the eye. Keratoplasty has been found to be a potent eye-s...

1. Letko E, Stechschulte SU, Kenyon KR, et al. Amniotic membrane inlay and overlay grafting for corneal epithelial defects and stromal ulcers. Arch Ophthalmol. 2001;119:659-663. 2. Ferreira De Souza R, Hofmann-Rummelt C, Kruse FE, Seitz B. Multilayer amniotic membrane transplantation for corneal ulcers not treatable by conventional therapy—a prospective study of the status of cornea and graft d...

When established corneal ulcers induced by alkali burning were treated with 10% ascorbate drops, no perforation occurred, in contrast to a 25% incidence in the control group. If perforations and descemetoceles were grouped together, these difference became insignificant (i.e., 14.2% ascorbate-treated vs. 25% control). Prolongation of descemetocele presence without perforation in the ascorbate-t...

Pseudomonas aeruginosa was isolated from the corneal scrapings of 11 of 14 patients with gram-negative corneal ulcers and fromi salt tablet-prepared saline solutions from 6 of these patients wearing soft contact lenses. Comparison of physiological properties, antibiograms, serotypes, and plasmid profiles for five of the patients indicated that the isolates from the ulcer and the saline solution...

A 71-year-old Chinese male was referred for severe dry eyes who suffered from multiple corneal melting ulcers and underwent a long-term and high-dosage interferon alpha-2b (INFα-2b) treatment for multiple myeloma (MM). The patient was diagnosed to have MM 12 years ago, and since then INFα-2b (3-million units, intramuscularly, three times a week) was prescribed until the present. Two years ago, ...

upper respiratory tract diseases (urtd) are common clinical problem in cats worldwide. feline calicivirus (fcv) and feline herpesvirus type 1 (fhv-1) are the main primary pathogens. feline immunodeficiency virus (fiv) and feline leukemia virus (felv) are also among the most common infectious diseases of cats which suppress the immunity. oropharyngeal and conjunctival swabs and blood samples wer...

INTRODUCTION Diabetic keratopathy is a rare complication of diabetes mellitus. This case illustrates the importance of checking blood sugar levels of patients with non-healing corneal ulcers to rule out the possibility of undiagnosed diabetes mellitus. CASE PRESENTATION We report the unusual case of a 24-year-old southeast Asian woman who presented with a sterile corneal ulcer to our hospital...

PURPOSE To compare the efficacy of topical cefazolin-gentamicin versus vancomycinceftazidime for treatment of bacterial corneal ulcers. METHODS This randomized double-masked clinical trial was performed on consecutive patients with bacterial corneal ulcers referred to Feiz Hospital, Isfahan, Iran from 2004 to 2005. Patients were randomly assigned to cefazolin-gentamicin or vancomycin-ceftazid...