QT dispersion (QTD) on 12-lead ECGs has been proposed as a marker of malignant ventricular tachyarrhythmias, and increased QTD has been reported in long QT syndrome (LQTS). On the other hand, it has been demonstrated that transmural dispersion is associated with ventricular tachyarrhythmias in an experimental model. However, the precise type of QTD or transmural dispersion that contributes most...

Background: Cigarette smoking has several known detrimental effect on cardiovascular system.  QT dispersion (QTd) is among the important predictors of cardiac death. Objective:  To assess the acute effect of smoking of a single standard cigarette on QT and QTc (corrected QT) dispersion, hence on the risk of ventricular arrhythmias in healthy smokers and non-smokers. Methods: 111 healthy men wit...

BACKGROUND Anthracyclines are important components of many chemotherapeutic protocols. The present study aimed to evaluate the repolarization changes in electrocardiography (ECG) which may predict drug induced arrhythmia. MATERIALS AND METHODS In this cross-sectional study, the recorded ECGs were assessed for QT dispersion (QTd), QT corrected dispersion (QTcd), T peak to Tend dispersion (TPed...

STUDY OBJECTIVE To evaluate the effects of methadone on QT-interval dispersion. DESIGN Single-center, prospective, cohort study. SETTING Methadone maintenance treatment facility. PATIENTS One hundred eighteen patients who were newly admitted to the facility. Intervention. Twelve-lead electrocardiograms (ECGs) were performed in patients at both baseline and 6 months after the start of meth...

Purpose: It is thought that arrhythmias are responsible for sudden deaths in patients with mitral valve prolapse (MVP). QT intervals may predict malignant arrhythmia potential in these patients. The aim of the present study is to assess QT variables in patients with MVP. Methods : We studied 46 patients with non-rheumatic, uncomplicated and isolated MVP and 25 healthy control subjects. All indi...

background: cigarette smoking has several known detrimental effect on cardiovascular system.  qt dispersion (qtd) is among the important predictors of cardiac death.   objective:   to assess the acute effect of smoking of a single standard cigarette on qt and qtc (corrected qt) dispersion, hence on the risk of ventricular arrhythmias in healthy smokers and non-smokers.   methods: 111 healthy me...

OBJECTIVE Fibromyalgia (FM) is a chronic disease characterized by widespread pain. Somatic complaints associated with the cardiovascular system, such as chest pain and palpitations, are frequently seen in FM patients. P and QT dispersions are simple and inexpensive measurements reflecting the regional heterogeneity of atrial and ventricular repolarization, respectively. QT dispersion can cause ...

Among childhood psychiatric disorders, attention deficit hyperactivity disorder (ADHD) is of greatest interest to practitioners. Methylphenidate (MPH) is a drug that is widely used in the treatment of children in whom ADHD has been diagnosed. Although this treatment has been used for years, its effects on the heart remain the subject of debate. The QT interval comprises the ventricular activati...

BACKGROUND Drug-induced increase in QT dispersion has been associated with potentially fatal ventricular arrhythmias. Little is known about the use of psychotropic substances, alone or in combination with other drugs on QT dispersion. OBJECTIVES To evaluate the impact of psychotropic drugs on QT interval dispersion in adults. METHODS An observational cohort study was designed involving 161 ...