Cloud computing offers a fast, easy and cost-effective way to configure and allocate computing resources for web applications, such as consoles for smart grid applications, medical records systems, and security management platforms. Although a diverse collection of cloud resources (e.g., servers) is available, choosing the most optimized and cost-effective set of cloud resources for a given web...

In order to reduce cost and improve efficiency, many data centers adopt virtualization solutions. The advent of virtualization allows multiple virtual machines hosted on a single physical server. However, this poses new challenges for resource management. Web workloads which are dominant in data centers are known to vary dynamically with time. In order to meet application’s service level agreem...

Cluster-based Web server systems have become a major means to hosting e-commerce sites. In this paper, we link the issue of resource partitioning scheme with the pricing strategy in a Service-Level-Agreement (SLA) and analyze the problem of maximizing the revenues attained in the hosting of a ecommerce site with a SLA contract by optimally partitioning the server resources among all supported s...

CE-MC server (http://cemc.sdsc.edu) provides a web-based facility for the alignment of multiple protein structures based on C-alpha coordinate distances, using combinatorial extension (CE) and Monte Carlo (MC) optimization methods. Alignments are possible for user-selected PDB (Protein Data Bank) chains as well as for user-uploaded structures or the combination of the two. The whole process of ...

With the rapid growth of the World Wide Web, clients attempting to access some popular web sites are experiencing slow response times due to server load and network congestion. Replacing the single server machine with a set of replicated servers is a cost-effective solution to partition server load which also allows incremental scalability and fault transparency. Distributing these replicated s...

SUMMARY The FAF-Drugs2 server is a web application that prepares chemical compound libraries prior to virtual screening or that assists hit selection/lead optimization before chemical synthesis or ordering. The FAF-Drugs2 web server is an enhanced version of the FAF-Drugs2 package that now includes Pan Assay Interference Compounds detection. This online toolkit has been designed through a user-...

The success of the World Wide Web measured in terms of the number of its users and of the resulting traffic increase is only commensurate to the patience required when sitting in front of one’s computer, waiting for a document to be down-loaded. If one could identify the typical access patterns for a set of documents on a Web server, the server could use or extend the existing protocols to acco...

We describe the design of a system for a fast and reliable HTTP service termed Web++. Web++ achieves high reliability by dynamically replicating Web data among multiple Web servers. Web++ selects a server which is available and that is expected to provide the fastest response time. Furthermore, Web++ guarantees data delivery, provided that at least one server containing the requested data is av...