BACKGROUND The economic merit of universal prophylaxis and preemptive therapy in the management of cytomegalovirus (CMV) infection for serology positive (R+) kidney transplant patients remains undefined. We performed cost effectiveness and cost utility modeling comparing these two approaches. METHODS The incidence of CMV infection under universal prophylaxis and preemptive therapy was determi...

Desired Saving Equals Desired Investment The theory says that the real interest rate r adjusts so desired saving S equals desired investment I (figure 1). As the real interest rate is the cost of capital to the firm, a lower real interest causes higher investment demand. And as the real interest rate is the return to saving, a higher real interest rate creates a greater incentive to save; and s...

E-procurement solutions can deliver great cost-saving potential for purchasing. But services have not generally been considered as a part of these cost-saving measures. The process of service procurement is often argued to be more complex and less standardized than material procurement. In this paper we propose solutions and standards for service procurement.

BACKGROUND We examined efficacy, toxicity, relapse, cost, and quality-of-life thresholds of hypothetical HIV cure interventions that would make them cost-effective compared to life-long antiretroviral therapy (ART). METHODS We used a computer simulation model to assess three HIV cure strategies: Gene Therapy, Chemotherapy, and Stem Cell Transplantation (SCT), each compared to ART. Efficacy an...