Bone regeneration is a complex, well-coordinated physiological process. Large quantities of bone regeneration are often required for craniofacial skeletal reconstruction of large bone defects created by trauma, tumor resection, infection, and skeletal abnormalities. Over the last two decades, a tissue engineering and regeneration approach has been developed as an alternative to conventional sur...

We introduce the Ontology of Craniofacial Development and Malformation (OCDM) as a mechanism for representing knowledge about craniofacial development and malformation, and for using that knowledge to facilitate integrating craniofacial data obtained via multiple techniques from multiple labs and at multiple levels of granularity. The OCDM is a project of the NIDCR-sponsored FaceBase Consortium...

Craniofacial registration is used to establish the point-to-point correspondence in a unified coordinate system among human craniofacial models. It is the foundation of craniofacial reconstruction and other craniofacial statistical analysis research. In this paper, a non-rigid 3D craniofacial registration method using thin-plate spline transform and cylindrical surface projection is proposed. F...

The computer-aided craniofacial reconstruction (CFR) technique has been widely used in the fields of criminal investigation, archaeology, anthropology and cosmetic surgery. The evaluation of craniofacial reconstruction results is important for improving the effect of craniofacial reconstruction. Here, we used the sparse principal component analysis (SPCA) method to evaluate the similarity betwe...

Engineering of craniofacial tissues would have a profound impact on various treatment strategies in dentistry. The role of mesenchymal stem cells in the formation of all craniofacial and dental structures has been well demonstrated. Stem cells from various craniofacial structures like dental epithelium, dental follicle, apical papilla, exfoliated deciduous teeth, periodontal ligament and dental...

Craniofacial disorders are one of the most common category of birth defects worldwide, and are an important topic of biomedical research. In order to better understand these disorders and correlate them with genetic patterns and life outcomes, researchers need to quantify the craniofacial anatomy. In this paper we introduce several different craniofacial descriptors that are being used in resea...