In this review, we analyze and illustrate the variation of the two main lead-like descriptors [molecular weight (MW) and the partition coefficient (logP)] in the generation of libraries in which a natural product (NP) is used as the guiding structure. Despite the different approaches used to create NP-like libraries, controlling these descriptors during the synthetic process is important to gen...

Enhancing the speed and competition in an exhibition of services and products motivated the companies to provide high-quality products to the customers. One of the effective strategies to reach these goals is to create working groups. These groups can help the companies to improve the quality and exposure of their services along with reducing the costs. This approach is applicable in the health...

This paper addresses an aspect of social environments comprising a series of processes that begin with an artificial agent (the “author-agent”) producing surprising products (objects, events, etc.), continue with other artificial agents (the “jury-agents”) appraising those products with respect to surprise (manifested, for instance, by the focus of their attention on those products), and end wi...

Art has generally been associated with aesthetics, emotion, and senses. On the contrary, mathematics logic, precision, truth. It is necessary to understand that throughout history, two disciplines have more united than many might consider. Various characteristics believed be antagonistic proved convergent divergent. Both use patterns, shapes, lines, fractions, proportions, etc. These concepts a...

Reactive architectures have gain wide acceptance as a robust and effective architecture design that yields results through the flexibility of its simplicity. Such architectures have made their way into many commercial products, including the popular iRobot Roomba vacuum cleaner. The existing reactive architecture does not always produce results efficiently and by adding mapping functions and pl...

In the context of Service-Oriented Computing, applications can be developed following the REST (Representation State Transfer) architectural style. This style corresponds to a resource-oriented model, where resources are manipulated via CRUD (Create, Request, Update, Delete) interfaces. The diversity of CRUD languages due to the absence of a standard leads to composition problems related to ada...

Context: Model-Driven Engineering provides a new landscape for dealing with traceability in software development. Objective: Our goal is to analyze the current state of the art in traceability management in the context of Model-Driven Engineering. Method: We use the systematic literature review based on the guidelines proposed by Kitchenham. We propose five research questions and seven quality ...