Total internal reflection fluorescence (TIRF) microscopy fluorescence— optical sectioning limiting the excitation volume to the close vicinity of the interface by sending the excitation light at an incident angle higher than the critical angle; usually implemented using a high numerical aperture (NA) objective. high signal-to-background for nearsurface structures monitoring plasma membrane proc...

The analysis of evoked potentials of sensorimotor cortex in response to electrical stimulation of n. ischiadicus shows that the extremal factor hypokinesia has a negative impact on the dynamics of formation of amplitudal and temporal characteristics since eyes openning in 2-weeks old rats. The most vulnerable process to the impact of hypokinesia is the first-positive phase, which disappears in ...

The analysis of evoked potentials of sensorimotor cortex in response to electrical stimulation of n. ischiadicus shows that the extremal factor hypokinesia has a negative impact on the dynamics of formation of amplitudal and temporal characteristics since eyes openning in 2-weeks old rats. The most vulnerable process to the impact of hypokinesia is the first-positive phase, which disappears in ...

It is widely recognized that balancing excitation and inhibition is important in the nervous system. When such a balance is sought by global strategies, few modes remain poised close to instability, and all other modes are strongly stable. Here we present a simple abstract model in which this balance is sought locally by units following "anti-Hebbian" evolution: all degrees of freedom achieve a...

Micron-size bubbles encapsulated by a stabilizing layer of surface-active materials are used in medical ultrasound imaging and drug delivery. Their destruction stimulated by ultrasound in vivo plays a critical role in both applications. We investigate the destruction process of microbubbles in a commercially available contrast agent by measuring the attenuation of ultrasound through it. The mea...

Data from a number of different experimental measurements have been used to construct caloric curves for five different regions of nuclear mass. These curves are qualitatively similar and exhibit plateaus at the higher excitation energies. The limiting temperatures represented by the plateaus decrease with increasing nuclear mass and are in very good agreement with results of recent calculation...

It is well known that a variety of cardiac arrhythmias are initiated by a focal excitation in heart tissue. At the single cell level these currents are typically induced by intracellular processes such as spontaneous calcium release (SCR). However, it is not understood how the size and morphology of these focal excitations are related to the electrophysiological properties of cardiac cells. In ...