Introduction This study aimed to investigate the preventive and therapeutic effects of crocetin (Cro) on ischaemic stroke in cell animal models. Material methods A model oxygen glucose deprivation (OGD) a rat middle cerebral artery occlusion were established simulate stroke. The infarct volume was measured by TTC assay, apoptotic number counted TUNEL. Relative protein gene expression levels rat...

ft-raman spectra of saffron (crocus sativus l.) with a partial assignment is reported. based on the raman data, it is concluded that main pigments in saffron are crocins and crocetin. it is proposed that the quickly attainable ft-raman spectrum of solid saffron, may be used as a means of saffron standardization.

In this study, volatile and bioactive compositions of saffron samples collected from Khorasani region in Iran Razavi different locations Turkey containing Hatay (Kırıkhan, Iskenderun, Hassa Yayladağı counties), Karabük (Safranbolu county Yukarıbucak Ovacuma villages), Ankara (Ayaş, Nallıhan Polatlı Çukurova (Adana-Cukurova, Mersin-Tarsus Osmaniye-Kadirli counties) Antalya (Korkuteli county) wer...

Crocus sativus L. (C. sativus), commonly known as saffron, is used as a food additive, preservative and medicinal herb. It has been considered as an alternative treatment for gastrointestinal diseases. C. sativus’ medicinal effects are associated to its major ingredients including crocin, crocetin and safranal. This study found that the gastrointestinal effects of C. sativus and its major ingre...

Crocus sativus L. (C. sativus), commonly known as saffron, is used as a food additive, preservative and medicinal herb. It has been considered as an alternative treatment for cardiovascular diseases. C. sativus’ medicinal effects are associated to its major ingredients including crocin, crocetin and safranal. This study found that the cardiovascular effects of C. sativus and its major ingredien...

Chloroplast Membranes, Lipid Peroxidation, Singlet Oxygen, H erbicide Dam age, Chloroplast Pigments The breakdown of chlorophylls, carotenoids, and linolenic acid together with the formation o f malondialdehyde and ethane was followed in isolated pea chloroplast membranes. Breakdown was enhanced by light, oxygen, D 20 and rose bengal, but retarded by crocetin. The results are discussed in relat...

Background: Inflammatory factors play an important role in cellular damage after shock and resuscitation. Crocetin, a saffron-derived carotenoid, has been shown to improve postshock recovery of cellular adenosine triphosphate (ATP) and to increase overall survival in an experimental model of hemorrhagic shock. The hypothesis of the present study is that treatment with crocetin at the beginning ...

saffron, the dried red-orange stigmas of crocus sativus l, has been known as a flavoring agent, food coloring and traditional herbal medicine. pharmacological effects of saffron are mainly attributed to crocin, crocetin, picrocrocin and safranal. these components especially crocin, have significant effects including antidepressant and anticonvulsant, analgesic, anti-cancer and other therapeutic...