A 20-year-old man with no prior complaints presented with progressive hyper pigmentation for 8 months, intermittent loose stools, hematochezia and vague abdominal pain. He also had anorexia and weight loss of 8 kg over last 8-mo. There was no family history of polyposis. On physical examination, he was lean, pale, had generalized hyperpigmentation, onychodystrophy [Figure 1] and alopecia. Initi...

INTRODUCTION Cronkhite Canada Syndrome (CCS) is a rare syndrome, described in 1955 by Americans, Leonard Wolsey Cronkhite and Wilma Jeanne Canada in the New England Journal of Medicine [1]. About 450 cases have been reported. Complications, like malignant transformation, unprovoked thromboembolism is known. Since there is wide variability in medical presentation, no definitive diagnostic and tr...

Cronkhite-Canada syndrome (CCS) is a rare non-familial disorder with multiple gastrointestinal polyps and ectodermal changes. Adenomatous and carcinomatous changes have been reported. Video capsule endoscopy is a useful non-invasive tool to reveal polypoid lesions of the gastrointestinal tract suspicious for malignancy. We report a case of a patient with CCS with excessively elongated intestina...