نتایج جستجو برای: crs
تعداد نتایج: 4118 فیلتر نتایج به سال:
BACKGROUND The prevalence of patients with chronic rhinosinusitis (CRS) refractory to traditional therapy appears to be on the increase. In these cases, CRS tends to be associated with bronchial asthma (BA), especially, aspirin-intolerant asthma (AIA). On the other hand, arachidonic acid metabolites have been extensively investigated in the pathogenesis of BA. We sought to assess the role of pr...
Objective—To determine the extent to which child restraint system (CRS) misuse can be evaluated by parental survey. Methods—A cross sectional survey was conducted at eight CRS clinics from May to October, 1998. Before CRS inspection, parents were administered a structured interview to identify distinct characteristics of restraint use and misuse. After the interview, a certified child passenger...
BACKGROUND A subset of patients with chronic rhinosinusitis (CRS) has refractory disease. The risk factors for refractory CRS include atopy, a disrupted mucociliary transport system, medical conditions affecting the sinonasal tract mucosa, and immunodeficiency. METHODS We review four primary immunodeficiencies reported in individuals with CRS: common variable immune deficiency (CVID), selecti...
OBJECTIVE Chronic rhinosinusitis (CRS) is a multifactorial inflammatory disease. In particular, CRS with eosinophilic features and/or nasal polyps (NPs) is often recalcitrant to current treatment; thus, appropriate animal models are mandatory to elucidate the pathogenesis of CRS and develop novel and efficient treatment modalities. The author reviewed the recently proposed animal models in CRS ...
BACKGROUND Congenital rubella syndrome (CRS) case identification is challenging in older children since laboratory markers of congenital rubella virus (RUBV) infection do not persist beyond age 12 months. METHODS We enrolled children with CRS born between 1998 and 2003 and compared their immune responses to RUBV with those of their mothers and a group of similarly aged children without CRS. D...
PURPOSE Asthma exacerbation from human rhinovirus (HRV) infection is associated with deficient antiviral interferon (IFN) secretion. Although chronic rhinosinusitis (CRS), an inflammatory upper airway disease, is closely linked to asthma, IFN-β responses to HRV infections in human nasal epithelial cells (HNECs) from CRS patients remain to be studied. We evaluated inflammatory and antiviral resp...
The innate immune system and its complex interplay with the adaptive immune system are increasingly being recognized as important factors in the pathogenesis of chronic rhinosinusitis (CRS). Adaptive immune components, including resident and inflammatory cells, and their associated mediators, have been the subject of most research in CRS. For this reason, theories of CRS pathogenesis have invol...
Chile was the first country in the Americas to conduct surveillance for congenital rubella syndrome (CRS) as part of screening for common causes of congenital birth defects (referred to as TORCH pathogens). The surveillance system identified 15 CRS cases in 1999 and 2 cases in 2000, and it has identified no CRS cases since 2000. CRS surveillance in Chile meets recommended surveillance standards...
Results The prevalence of ARS is significantly related to AR, a doctor’s diagnosis of CRS, urticaria, eczema, smoking, gender, ethnicity and age. The prevalence of CRS is significantly related to AR, a doctor’s diagnosis of CRS, urticaria, adverse response to painkiller, smoking, ethnicity, asthma and age. The prevalence of AR is significantly related to a doctor’s diagnosis of CRS, urticaria, ...
background chronic rhinosinusitis (crs) and asthma are among the most important health-related conditions with evident socio-economic effects. the relationship between asthma and crs has been considered in medical references for centuries. previous studies have shown that treatment interventions targeting disease in one part of the airway are effective for general asthma management. however, th...
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