نتایج جستجو برای: crtm
تعداد نتایج: 63 فیلتر نتایج به سال:
The isoprenoid biosynthesis pathways produce the largest class of small molecules in Nature: isoprenoids (also called terpenoids). Not surprisingly then, isoprenoid biosynthesis is a target for drug discovery, and many drugs--such as Lipitor (used to lower cholesterol), Fosamax (used to treat osteoporosis), and many anti-infectives--target isoprenoid biosynthesis. However, drug resistance in ma...
Staphylococcus aureus produces a golden carotenoid virulence factor called staphyloxanthin (STX), and we report here the inhibition of the enzyme, dehydrosqualene synthase (CrtM), responsible for the first committed step in STX biosynthesis. The most active compounds are halogen-substituted phosphonosulfonates, with K(i) values as low as 5 nM against the enzyme and IC(50) values for STX inhibit...
Protocol sequences are binary and periodic sequences used for deterministic multiple access in a collision channel without feedback. In this paper, we focus on user-irrepressible (UI) protocol sequences that can guarantee a positive individual throughput per sequence period with probability one for a slot-synchronous channel, regardless of the delay offsets among the users. As the sequence peri...
The Microsized Microwave Atmospheric Satellite (MicroMAS-2A) is a 3U CubeSat that was launched in January 2018 as technology demonstration for future microwave sounding constellation missions, such the NASA Time-Resolved Observations of Precipitation structure and storm Intensity with Constellation Smallsats (TROPICS) mission now development. MicroMAS-2A has miniaturized 1U ten-channel passive ...
Although it is known that a part of lactic acid bacteria can produce carotenoid, little is known about the regulation of carotenoid production. The objective of this study was to determine whether aerobic growth condition influences carotenoid production in carotenoid-producing Enterococcus gilvus. Enterococcus gilvus was grown under aerobic and anaerobic conditions. Its growth was slower under...
The bulk-scattering properties of dust aerosols and clouds are computed for the community radiative transfer model (CRTM) that is a flagship effort of the Joint Center for Satellite Data Assimilation (JCSDA). The delta-fit method is employed to truncate the forward peaks of the scattering phase functions and to compute the Legendre expansion coefficients for re-constructing the truncated phase ...
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