OBJECTIVES To define the patient-reported complications after cryoablation therapy for prostate cancer and to compare these results to previously published patient-reported complications for radical prostatectomy and external beam irradiation. METHODS A questionnaire similar to previously published patient-reported complication studies was sent to the first 290 patients treated by cryoablatio...

AIMS Radiofrequency (RF) catheter ablation in the septum close to the atrioventricular (AV) node or His bundle has an increased risk of irreversible complications. Cryothermal energy has the advantages of reversible cryomapping and increased catheter stability. This study evaluates the usefulness of cryoablation in superoparaseptal and septal accessory pathways (APs). METHODS AND RESULTS Twen...

BACKGROUND Percutaneous cryoablation is a minimally invasive alternative for surgical resection of a renal tumor. We report our experience with applying computed tomography-guided cryoablation in renal tumors, focusing on the technique, safety, and treatment response. METHODS We retrospectively reviewed the medical records of patients who received cryoablation from October 2009 to August 2013...

Over the last decade, cryoballoon ablation has emerged as an effective alternate strategy to point-by-point radiofrequency ablation for treatment of symptomatic atrial fibrillation. There are several reasons for this. First, the acute and long-term safety and efficacy associated with cryoablation appear comparable to that of radiofrequency ablation in patients with both paroxysmal and also pers...

OBJECTIVE This study is to investigate the in vivo apoptotic processes in glioma tissues following cryoablation and the effects of glioma tissue extracts on GL261 glioma cells in vitro. METHODS TUNEL and flow cytometry analysis were performed to detect the apoptotic processes in the glioma tissues following cryoablation and in the GL261 cells treated with cryoablated tumor extracts. The scrat...

Targeted cryoablation of the prostate has evolved significantly since its reintroduction in the early 1990s. This evolution stems from engineering advancements, procedural refinement, introduction of temperature monitoring, and greater understanding of cryobiology. Recent publications demonstrate durable efficacy for cryoablation, equivalent to other therapies for low-risk disease and possibly ...

OBJECTIVE Traumatic amputation at the pelvic level is a rare procedure with few studies addressing long-term complications. Painful neuroma formation may form at the site of nerve transection and cause significant impairments in daily living. Ultrasound-guided cryoablation therapy has grown in popularity and should be considered in patients with painful neuromas. This is a case report of comple...

OBJECTIVE To explore the inhibiting effect and mechanism of Endostar injection concomitant with cryoablation on lung adenocarcinoma A549 xenografts in nude mice. MATERIALS AND METHODS A total of 24 nude mice with subcutaneous xenografts of the A549 cell line were established and divided into 4 groups when the maximal diameters of tumors became 1 cm: control group, Endostar group, cryoablation...

Dual atrioventricular nodal nonreentrant tachycardia (DAVNNT) is a rare tachycardia in which dual AV nodal physiology allows for a single sinus complex to conduct down both the fast and slow AV nodal pathways, resulting in 2 ventricular depolarizations. A recent review of the literature surrounding DAVNNT identified only 68 published cases. All ablations have been performed via radiofrequency a...

Antigen-specific DNA vaccine immunotherapy is an attractive approach for the treatment of cancer since it has the potency to specifically eradicate systemic tumors without damaging the normal cells. However, DNA vaccine shows insufficient immune response for antigen presenting cells and has minimal clinical efficacies. Cryoablation therapy is the therapeutic application of extreme cold for loca...