Eighteen patients (mean age of 66.5 years) with normal pressure hydrocephalus (NPH) underwent a ventriculo-peritoneal shunt surgery. Prior to operation a cerebrospinal fluid tap-test (CSF-TT) was performed with measurements of gait pattern and psychometric functions (memory, visuo-motor speed and visuo-constructive skills) before and after the removal of 50 ml CSF by lumbar puncture (LP). Fifte...

BACKGROUND AND PURPOSE There is limited evidence to support the use of high-volume lumbar taps over lower-volume taps in the diagnosis of normal pressure hydrocephalus. The purpose of this study is to detect whether the volume of CSF removed from patients undergoing high-volume diagnostic lumbar tap test for normal pressure hydrocephalus is significantly associated with post-lumbar tap gait per...

BACKGROUND The polymerase chain reaction (PCR)-based test to detect herpes simplex virus (HSV) genome in cerebrospinal fluid (CSF) has become the test of choice for diagnosing this infection. The utility of this test in young infants undergoing sepsis evaluations is unknown. OBJECTIVES We sought to identify the factors that prompted physicians to include HSV PCR in their evaluation of young i...

INTRODUCTION Determining the presence or absence of red blood cells (RBC) or their breakdown products in cerebrospinal fluid (CSF) is essential for the evaluation of subarachnoid hemorrhage (SAH) in headache patients. Current methodology for finding blood in the CSF is either spectrophotometric detection of pigment, which is time consuming and labor intensive, or visual assesment of samples for...

The Amplicor Enterovirus PCR test was compared with viral culture for the detection of enteroviruses in cerebrospinal fluid (CSF) specimens. In a multicenter study in which nine laboratories participated, a total of 476 CSF specimens were collected from patients with suspected aseptic meningitis. Sixty-eight samples were positive by PCR (14.4%), whereas 49 samples were positive by culture (10.4...

PURPOSE To compare the chromatic contrast sensitivity function (CSF) for the blue-yellow opponent channel (BYOC) between female badminton players and non-athlete controls. METHODS We recruited 40 young females (18-25 years old) who played badminton for at least 5 consecutive years as the test group, and 30 age-matched female controls who had no history of regular physical activity. The Patter...

The present work aimed to evaluate the pattern of CSF alterations in patients diagnosed with neurocysticercosis (NCC) in racemose form.Method This is a retrospective cohort study of patients with diagnosis of NCC in racemose form. CSF samples from 26 patients were analyzed. After patient-chart analysis was performed descriptive analysis of case studies and comparison between sexes in relation t...

INTRODUCTION The study aimed to determine the room for improvement of a perfect cerebrospinal fluid (CSF) biomarker and the societal incremental net monetary benefit of CSF in subjects with mild cognitive impairment (MCI) assuming a hypothetical disease-modifying Alzheimer's disease (AD) treatment. METHODS A decision model compared current practice to a perfect biomarker and to two strategies...

The western blot (WB) for S. neurona performed on serum and spinal fluid (CSF) is widely used for antemortem diagnosis of neurologic disease and for screening normal horses. Because CSF collection is difficult, the WB is often performed on the more readily available serum sample only. However, seroprevalence to S. neurona is high in normal horses and studies to evaluate the blood test have not ...

This work determines the spatial and temporal distribution of cerebrospinal fluid (CSF) pressure and brain displacement during an infusion test in a spherically symmetric model of the brain. The response of CSF pressure and parenchymal displacement to blood pressure pulsations is determined in the solution. We use a spherically symmetric, three-component poroelastic model of the brain, differen...