نتایج جستجو برای: cutaneous basophil hypersensitivity
تعداد نتایج: 91842 فیلتر نتایج به سال:
Non-steroidal anti-inflammatory drugs (NSAIDs) are the most common cause of hypersensitivity reactions, with pyrazolones the most frequent drugs inducing selective reactions. Immediate selective hypersensitivity to pyrazolones is thought to be mediated by specific-IgE. Sensitivity of in vitro diagnostic tests is low and this may be due to the incomplete characterization of the structures involv...
PURPOSE Cefaclor is widely prescribed for various infectious diseases. As its consumption increases, the number of hypersensitivity reactions to cefaclor has increased. This study aimed to evaluate the immunologic findings of immediate hypersensitivity to cefaclor. MATERIALS AND METHODS We enrolled 47 patients with immediate hypersensitivity to cefaclor from Ajou University Hospital and Asan ...
BACKGROUND 2D7 and BB1 are thought to be basophil-specific markers. In this study, we tested both antibodies in different skin and mast cell disorders with the aim of determining whether it was possible to differentiate between benign and aggressive presentations of mastocytosis. METHODS Using the antibodies 2D7, BB1, and c-Kit, we performed an immunohistochemical study of skin biopsy specime...
Chlorpheniramine is a widely prescribed H1-antihistamine for relieving urticaria or histamine-mediated allergic reactions. However, although rare, it may cause immediate hypersensitivity reactions. The diagnosis is usually made by provocation test, but its application is often limited due to comorbidities or potential risk of severe reactions. In those cases, skin tests and basophil activation ...
Methods We present 8 children with suspected hypersensitivity reaction after parenteral MP (6 children), DX inhalation (1 child) and inhafluticasone propionate (FL) (1 child). Prick and intradermal skin testing with MP, HC, DX and FL were performed. In case of negative skin tests provocation tests were performed. Basophil activation test (flow cytometry analyses of basophil CD63 surface express...
BACKGROUND We present the results obtained from the largest series of in vitro diagnostic tests ever reported in patients with clinically validated hypersensitivity to acetylsalicylic acid (ASA)/nonsteroidal anti-inflammatory drugs (NSAID) compared with various categories of controls tolerating ASA/NSAIDs. This multicenter study, which was performed within the framework of the European Network ...
Antigen-mediated stimulation of thymidine incorporation was demonstrated in lymph node cells from guinea pigs immunized with 100 microg human serum albumin in either Freund's incomplete or Freund's complete adjuvant. Animals receiving HSA in IFA exhibited both cutaneous basophil (Jones-Mote) hypersensitivity and lymphocyte stimulation at 1, but not at 6 wk after immunization. Significant stimul...
زمینه مطالعه: تعیین نیاز انرژی مرغان بومی کشور و بخصوص تاثیر آن برسیستم ایمنی از اولویت های پژوهشی در جهت استفاده بهینه محسوب می شود. هدف: هدف از این مطالعه تعیین اثر سطوح مختلف انرژی متابولیسمی جیره بر توانایی تولید و ایمنی مرغان بومی بوده است. روش کار: از طــرحــی کــامـلاً تـصــادفــی بــا 6 تـیـمــار، 5 تـکــرار و 10 مـشــاهــده در هــر واحــد آزمــایشـی استفـاده شـد. تیمـارهـا جیـره هـایـی ...
Non-steroidal anti-inflammatory drugs (NSAIDs) are associated with type I hypersensitivity, including cutaneous manifestations (e.g., urticaria and angioedema), respiratory manifestations (rhinitis, nasal polyposis, asthma), and anaphylaxis. To assess the sensitivity/specificity of in vitro tests for verifying the causative/tolerant drugs and crossreactivity of different NSAIDs, we used three a...
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