Sarcoidosis is an autoimmune disease of unknown etiology characterized by the presence of non-caseating epithelioid cell granulomas in multiple organs. Cutaneous sarcoidosis occurs in approximately 25% of the cases. Sarcoid reactions on old scars, traumatized skin sites and around embedded foreign material have long been observed. For the past 70 years, sarcoidal granulomas on tattoos and perma...

We report on the successful treatment of nodular cutaneous sarcoidosis lesions using a flashlamp pumped pulsed dye laser (FPDL). After a test treatment session with FPDL, we were able to achieve complete remission of the treated skin lesions. The nontreated areas increased in size and served as a control. The patient has since undergone further treatments of the remaining areas, with complete c...

D. Dias Carlson, and Murphy. Drafting of the manuscript: G. D. Dias Carlson. Critical revision of the manuscript for important intellectual content: J. A. Carlson, Murphy, and Rohwedder. Statistical analysis: J. A. Carlson and G. D. Dias Carlson. Obtained funding: J. A. Carlson. Administrative, technical, and material support: J. A. Carlson and Murphy. Study supervision: J. A. Carlson. Financia...

Quiz 1. What is the diagnosis? 2. Describe the characteristic patterns shown in the Gallium-67 scan (Fig. 2). 3. Skin lesions occur in 75% of patients with this condition. Is this true or false? 4. Lesions respond to treatment with corticosteroids. Is this true or false? 5. Spontaneous remissions occur in nearly two-thirds of patients, but the course is chronic or progressive in 10% to 30%. Is ...

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Sarcoidosis is a multiorgan granulomatous disease in which the skin is one of the frequently involved target organs. Cutaneous involvement occurs in a third of patients with sarcoidosis and has protean manifestations. More than a century has passed since the initial description of sarcoidosis, but its cause continues to be an enigma. Recent studies have introduced several new insights into the ...

We report a case of interstitial keratitis and progressive hearing loss in a young female patient with biopsy proven cutaneous sarcoidosis. This rare sequence of ophthalmological and auditory signs in sarcoidosis mimicks Cogan's syndrome.

3D HFU: 3-dimensional high-frequency ultrasound scan CSAMI: Cutaneous Sarcoidosis Activity and Morphology Instrument PET/CT: positron emission tomography/ computed tomography C utaneous involvement occurs in 25% to 30% of patients with sarcoidosis. Effective treatment of the disease has historically been challenging given a lack of an objective, reproducible marker of disease activity. Here we ...

Reactivation of pre-existing scars, as a manifestation of cutaneous sarcoidosis, is uncommon and the clinical significance of this odd symptom often remains unrecognised. In the appropriate setting a skin biopsy may serve to establish the diagnosis of sarcoidosis and avoid more invasive attempts at obtaining tissue. The case of a 72 year old man with remote reactivation of multiple cutaneous sc...

Infiltration of sarcoid granuloma in old cutaneous scars is one of the uncommon cutaneous manifestations of sarcoidosis. Here, we report the case of a 47-year-old female who presented with swelling and irritation in 5 old scars. She had acquired these scars 9 years ago in a traffic accident. An incisional scar biopsy revealed noncaseating granulomas consistent with sarcoidosis. High-resolution ...