smoking has been shown to be a complicating factor in normal wound healing. both nicotine and carbon monoxide adversely affect multiple stages of the healing process. from 1991 to 1999,407 muscle flap procedures were performed on 374 patients in a single surgical unit. a retrospective review of 261 patients was completed. patients were divided into three groups: group a, no smoking history grou...

Introduction: Reconstruction of intraoral soft tissue defects is important in restoring function and esthetic. In large defects, there will be demand for regional pedicle flaps or free flaps. Hard palate separates nasal and oral cavities. Due to the small surface area between flap and remaining palate after surgical resections, optimal blood supply of the flaps for hard palate reconstructions ...

despite all modern surgical techniques, skin flap that is considered as the main method in most reconstructive surgeries puts the skin tissue at danger of necrosis and apoptosis derived from ischemia. therefore, finding a treatment for decreasing the apoptosis derived from flap ischemia will be useful in clinic. in present study, we evaluated the effect of azelaic acid 20% and finasteride on ex...

background: skin flap grafting is a popular approach for reconstruction of critical skin and underlying soft tissue injuries. in a previous study, we demonstrated the beneficial effects of two 5α-reductase inhibitors, azelaic acid and finasteride, on tissue survival in a rat model of skin flap grafting. in the current study, we investigated the involvement of nitric oxide and inducible nitric o...

Background: Lip carcinoma is a common cancer with a good prognosis and when patients refer early in the course of disease the results of treatment are acceptable. Surgical procedures for reconstruction of lip defects are the use of remaining lip tissue, tissue from the opposite lip, adjacent cheek tissue, distant flaps and microvascular free flaps. The bitemporal (visor) flap is a regional...

Introduction: Advanced lip carcinomas can invade adjacent structures. Performing surgery for these cancers will lead to defects in this anatomically and functionally important area and will cause post-op difficulties such as drooling, speech alterations and aesthetic considerations, if not properly managed. Case Report: In this study, we will introduce a radial forearm free flap with palmari...

BACKGROUND Post-burn contractures are a commonly encountered problem and many techniques have been described in their treatment. Z-plasties are the commonest local flap procedure done for linear bands with adjacent healthy tissue. Our aim was to assess the use of square flap technique in axillary contractures. METHODS Ten patients with type I and II axillary contractures underwent release by...

The pedicled anterolateral thigh (ALT) flap based on septocutanous or musculocutanous perforators of the lateral circumflex femoral system is a reliable flap. The use of ALT flap as a pedicled flap is relatively unpopular if compared with its use as a free flap. The flap can be raised as a fasciocutaneous or muscle flap or myocutaneous flap. The pedicled flap has got a lengthy pedicle with a li...