Vascular smooth muscle cells (VSMCs) are exposed to hormonal and mechanical stress in vivo. Hormonal factors have been shown to affect hypoxia-inducible factor-1alpha (HIF-1alpha). How mechanical stress affects the regulation of HIF-1alpha in VSMCs has not been reported previously, and therefore we sought to investigate the regulation of HIF-1alpha by cyclical mechanical stretch in cultured rat...

The paper presents a family of cycloidal cyclical surfaces, which are created by a movement of a circle alongside the special spatial cycloidal curve, where the circle is located in the curve normal plane and its centre is on this curve. The spatial cycloidal curve can be created by simultaneous revolution of a point about three different axes 3o,2 o and 1o in the space. The form of the cycloid...

I propose a method to estimate cyclical DSGE models using the raw data. The approach links the observables to the model counterparts via a ‡exible speci…cation which does not require that the cyclical component is solely located at business cycle frequencies and allows the noncyclical component to take various time series patterns. Applying standard data transformation induces distortions in st...

Bronchoconstrictor responses are quantitatively different when they are evoked under static conditions and during or after periods of deep inspiration. In vivo, deep inspirations produce bronchodilation and protect the lung from subsequent bronchoconstriction (termed bronchoprotection). These effects may be due in part to dynamic stretch on airways produced by cyclical expansion of airway diame...

It is common to assume in business cycle analysis that the capital stock is homogenous and constant in aggregate value. We explore the alternative concept that capital is heterogeneous, and whether it exhibits cyclical changes. A multiperiod model of investment implies that acquisition of specific components of capital responds to changes in relative interest rates, and we further show that the...

The understanding of the cause and treatment of premenstrual disorders is confused but it is essentially the result of cyclical ovarian activity, usually ovulation, and an effective treatment should be by suppressing ovulation. This can be done by an oral contraceptive but as these women are progestogen intolerant the symptoms may persist becoming constant rather than cyclical. Alternatively, t...

Whenever unemployment stays high for an extended period, it is common to see analyses, statements, and rebuttals about the extent to which the high unemployment is structural, not cyclical. This essay views the Beveridge curve pattern of unemployment and vacancy rates and the related matching function as proxies for the functioning of the labor market and explores issues in that proxy relations...

Both hyperprolactinemia and depressive disorder are known manifestations of hypothyroidism. However, hyperprolactinemia with overt symptomatology per se has not been reported to precede all episodes of organic depressive disorder. We report a similar presentation.

We consider a certain combinatorial game on a digraph for two cases of the price function. For one case the game in question extends the cyclical game studied in [1,2] which, in its turn, is a generalization of the well-known problem of finding a minimum mean cycle in an edge-weighted digraph. We prove the existence of optimal uniform stationary strategies for both cases and give algorithms to ...