The efficiency of the traditional DDFS is greatly depends on the large size of memory. The ROM less architecture for generating sine wave and its necessary corrective measure based on parabola has already been developed. This paper proposes a modified parabola by adding a triangular wave to achieve a sine wave with less distortion. This architecture gives better performance.

BACKGROUND Controversy exists as to whether patients with thick (Breslow depth>4 mm), clinically lymph node-negative melanoma require sentinel lymph node (SLN) biopsy. The authors examined the impact of SLN biopsy on prognosis and outcome in this patient population. METHODS A review of the authors' institutional review board-approved melanoma database identified 293 patients with T4 melanoma ...

PURPOSE The aim of the study was to explore the value of analyzing bone marrow (BM) for the presence of isolated tumor cell(s) (ITCs) in disease-free breast cancer patients 3 years after diagnosis. EXPERIMENTAL DESIGN ITCs in BM at operation was found to be an independent prognostic factor in 817 breast cancer patients. Among these, 356 disease-free patients were analyzed with a second BM aft...

This paper introduces a new approach to direct digital frequency synthesis (DDFS) based on the Coordinate Rotation (CORDIC) algorithm. The modifications to the standard CORDIC algorithm introduced in this paper allow fine frequency resolution, and exhibit significant potential for low power applications. The new architecture does not need a large ROM and can be implemented on a general purpose ...

A radiation-hardened 12-bit non-linear DAC was designed and fabricated on Honeywell’s 0.35 μm MOI5 SOI CMOS process. The non-linear DAC allows a significant reduction in complexity and power dissipation when used within direct digital frequency synthesizers (DDFSs). The non-linear DAC implements a 32-segement piecewise linear approximation to sine function reducing the ROM look-up table size fr...

This paper presents high speed direct digital frequency synthesizer (DDFS) based on pipelining phase accumulator (PA). The proposed 12-bit PA contains three pipelining stages with 4-bit carry-lookahead adder (CLA) with the carries ripple between these stages. Comparing results between similar phase accumulator designed with ripple carry adder on, Cyclone III FPGA platform reveals that the propo...

A scheme of frequency hopping spread spectrum (FHSS) frequency synthesizer suitable for synthesis of radio-frequency (RF) carrier signal in very high frequency (VHF) band is proposed, implemented and tested. The synthesizer is based on the direct digital frequency synthesis (DDFS or DDS) and phase locked loop (PLL) with dynamic monitoring of varicap’s voltage to reduce switching time. The resul...

BACKGROUND We examined the assumption in conventional teaching about metastatic adenoid cystic carcinoma (ACC) being an indolent type of disease. METHODS A single center analysis of 105 cases of ACC was performed. Radiographs were reviewed and tumor response to chemotherapy was measured. Distant disease-free survival (DDFS) and time to death since distant metastases diagnosis were analyzed. ...