In vivo microdialysis was used to examine the effect of two new catechol-O-methyltransferase (COMT) inhibitors, Ro 40-7592 and OR-611, on extracellular levels of dopamine, dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA), and 5-hydroxyindoleacetic acid (5-HIAA) in rat striatum. The interactions of the COMT inhibitors with nomifensine, clorgyline and deprenyl were also studied. Ro 40-...

This corrects the article on p. 611 in vol. 35, PMID: 26354349.

JADA, Vol. 136 www.ada.org/goto/jada May 2005 611 Restoration of

researchers within the last few decades because of its great potential utility for rapid drug delivery. It offers an attractive alternative for drugs that have limited oral bioavailability, are destroyed by gastrointestinal (GI) fluid, or are highly susceptible to hepatic first pass or gut-wall metabolism. Nasal drug delivery also offers the convenience and safety of noninvasiveness. In additio...

Keloids are benign fibroproliferative tumors with features of raised scar tissue and excessive growth beyond the original border. Keloid scars show extracellular matrix(ECM) deposition rich vasculature. Recently, many studies have revealed important pathways keloid pathogenesis. Herein, we focus on difference between traumatic nontraumatic keloids in a transcriptomic level. To preclude intra-le...

INTRODUCTION ............................................................................................... 609 I. BACKGROUND ..................................................................................... 611 A. Organ Transplantation in the United States ................................ 611 B. The HOPE Act ............................................................................. 615...

Patients 611 patients between 30 and 70 years of age who had type 2 diabetes; hypertension defined as systolic blood pressure > 135 mm Hg or diastolic blood pressure > 85 mg, or both; persistent microalbuminuria defined as an albumin excretion rate of 20 to 200 ìg/minute; and a serum creatinine concentration < 133 ìmol/l for men or < 97 ìmol/l for women. Exclusion criteria were non-diabetic kid...

THE AFTERLIFE OF “LITTLE WOMEN,” by Beverly Lyon Clark. Baltimore: Johns Hopkins University Press, 2014. 271 pp. $44.95 cloth; $44.95 ebook. TURNING THE PAGES OF AMERICAN GIRLHOOD: THE EVOLUTION OF GIRLS’ SERIES FICTION, 1865-1930, by Emily Hamilton-Honey. Jefferson, NC: McFarland, 2013. 254 pp. $45.00 paper; $45.00 ebook. READING LIKE A GIRL: NARRATIVE INTIMACY IN CONTEMPORARY AMERICAN YOUNG A...