نتایج جستجو برای: degarelix

تعداد نتایج: 125  

2017
Seiichiro Ozono Taiji Tsukamoto Seiji Naito Yasuo Ohashi Takeshi Ueda Tsutomu Nishiyama Hideki Maeda Hidehito Kusuoka Rio Akazawa Mototsugu Ito Hideyuki Akaza

Objective To evaluate the efficacy and safety of degarelix 3-month depot in Japanese patients with prostate cancer. Methods In this Phase II, open-label, parallel-group study, 155 Japanese prostate cancer patients were randomized to treatment with degarelix administered subcutaneously at a maintenance dose of 360 or 480 mg every 84 days for 12 months, after receiving an initial dose of 240 mg...

2017
Harri Visapää

INTRODUCTION Luteinizing hormone-releasing hormone (LHRH) analogues are widely used for the treatment of advanced hormone-dependent prostate cancer. However, there are currently no clinical guidelines for switching between LHRH analogues. It has been reported that there may be clinical benefits for patients switching between different formulations of LHRH agonists, as well as from an LHRH agoni...

Journal: :Cochrane Database of Systematic Reviews 2017

2015
Shawn Y. Ong Josephine Taverna Clint Jokerst Thomas Enzler Emad Hammode Elisa Rogowitz Myke R. Green Hani M. Babiker

Disseminated intravascular coagulation (DIC) with excessive fibrinolysis (XFL) is a rare and acute life-threatening variant of DIC in patients with prostate cancer. Patients present with coagulopathy, hypofibrinogenemia, and systemic bleeding. We describe a case of DIC XFL caused by prostate cancer (PC) successfully treated with a single injection of degarelix, a gonadotropin-releasing hormone ...

Journal: :Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica 2012
Filiberto Zattoni

The latest EAU guidelines on the evidence based-management of prostate cancer (P.Ca.), with regard to pharmacological androgen deprivation therapy (ADT), reiterate that the primary objective of hormonal therapy is to slow down the progression of the disease to the greatest possible extent. Degarelix a new product for the treatment of hormone-dependent P.Ca. has recently become available in Ital...

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