PURPOSE OF REVIEW Pediatric inflammatory demyelinating central nervous system diseases comprise monofocal and potentially monophasic disorders like optic neuritis and transverse myelitis, the multifocal, self-limiting disorder of acute disseminated encephalomyelitis, and multifocal chronic diseases like relapsing neuromyelitis optica and multiple sclerosis. This review discusses characteristics...

Multiple sclerosis is a chronic autoimmune demyelinating disease, one of the most common symptoms which are urinary disorders. The review article provides information on epidemiology, pathogenesis, symptoms, clinical course and diagnostic features neurogenic dysfunctions lower tract in patients with multiple sclerosis. Attention drawn to need for early diagnosis dysfunctions, predetermines time...

Peripheral neuropathies are among the most common diseases encountered in clinical neurology. Autoimmunity and inflammation are implicated in a small but important group of peripheral nerve disorders because they are potentially treatable. These include the acute inflammatory neuropathies grouped under Guillain-Barré syndrome (GBS) and the chronic inflammatory demyelinating polyradiculoneuropat...

Inflammatory demyelinating diseases comprise a spectrum of disorders affecting the myelin of the central and peripheral nervous system. These diseases can usually be differentiated on the basis of clinical, radiological, laboratory and pathological findings. Recent studies have contributed to current awareness that inflammatory demyelinating diseases are not restricted to the adult age group, b...

The acquired demyelinating polyneuropathies include acute (AIDP, Guillain-Barre syndrome, GBS) and chronic (CIDP, dysproteinemic) forms which differ primarily in their temporal profile. They are inflammatory-demyelinating diseases of the peripheral nervous System and likely have an immunologic pathogenesis. Although these neuropathies usually have a characteristic presentation, the electromyogr...

Demyelinating diseases alter myelin or the coating surrounding most nerve fibers in central and peripheral nervous systems. The grouping of human system demyelinating disorders today includes multiple sclerosis (MS) neuromyelitis optica spectrum (NMOSD) as distinct disease categories. Each is caused by a complex combination genetic environmental variables, many involving an autoimmune response....

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system, in which movement disorders (MD) have been reported very rarely. Anatomopathological studies of MS indicate two main processes: inflammation and neurodegeneration. The occurrence of the movement disorders symptoms in MS revises the question of aetiology of these two diseases. During the 10 yea...