STATEMENT OF THE PROBLEM The prevalence of overweight and obesity has been increasing markedly in recent years. It may influence growth in pre pubertal children. PURPOSE The purpose of this study was to determine whether increased Body Mass Index (BMI) is associated with accelerated skeletal maturation and dental maturation in six to fifteen years old orthodontic patients in Shiraz, Iran. M...

Dental caries continues to be the most prevalent bacteria-mediated non-contagious disease of humankind. Dental professionals assert the disease can be explained by poor oral hygiene and a diet rich in sugars but this does not account for caries free individuals exposed to the same risk factors. In order to test the hypothesis that amount of amelogenin during enamel development can influence car...

The discovery of dental stem cells received extensive attention because of its significance for the development of novel cellular therapies in dentistry. However, dental stem cells are also excellent for studies about cellular processes during dental tissue development or regeneration. Multipotent undifferentiated cells in the dental follicle (DFCs) are one example of dental stem cells. These c...

the present report aimed to study an uncommon case of a pair of twins that presented a discordant dental phenotype. family investigation, clinical, radiographic examination and molecular analysis were performed in both girls. molecular analysis confirmed the monozygosity by deoxyribonucleic acid chip technology. one twin presented tooth agenesis in left upper lateral incisor and peg-shaped on t...

Teeth are vertebrate organs that arise from complex and progressive interactions between an ectoderm, the oral epithelium and an underlying mesenchyme. During their early development, tooth germs exhibit many morphological and molecular similarities with other developing epithelial appendages, such as hair follicles, mammary and salivary glands, lungs, kidneys, etc. The developing mouse tooth g...

Humans' prolonged somatic development and life history are unique among primates, yet their evolutionary origins remain unclear. Dental development has been used as a proxy to reconstruct life history evolution in the hominin clade and indicates a recent emergence of the human developmental pattern. Here, we analyse tooth formation and eruption in two developing dentitions of Homo naledi, a lat...

AIM The aim of the study was to investigate potential differences between the physical development and the dental age in two groups of male pupils from two schools with different socio-economic profiles in the city of Torun (Poland). MATERIALS AND METHODS A total number of 286 school boys (age: 9-12 years) was examined: Group A consisted of 104 pupils of a private school (mean age: 10.36-/+0....

There has been rapid progress recently in the identification of signalling pathways regulating tooth development. It has become apparent that signalling networks involved in Drosophila development and development of mammalian organs such as the limb are also used in tooth development. Teeth are epithelial appendages formed in the oral region of vertebrates and their early developmental anatomy ...

Familial or X-linked hypophosphatemic rickets (XLHR) is the most common type of rickets in developed countries today. While the dental manifestations of rickets are well reported, there is little information regarding its relationship to dental development and other dental anomalies. This investigation studied the rate of dental development and associated dental anomalies in 19 XLHR subjects co...