Human deciduous and permanent teeth exhibit different developmental processes, morphologies, histological characteristics and life cycles. In addition, their pulp tissues react differently to external stimuli, such as the pulp sensitivity test, dental trauma and pulp therapy materials. These suggest differences in gene expression and regulation, and in this study we compared gene-expression pro...

Considering the ease of isolation and high expansion potential of pulp stem/progenitor cells isolated from wisdom and primary teeth they have been implicated as the most reliable autologous cell source in dental tissue engineering. Meanwhile, different isolation methods have remarkable impacts on the expansion potential of adult stem cells. In enzymatic digestion method extracted teeth as denta...

this article describes successful use of calcium-enriched mixture (cem) cement and biodentine in apexogenesis treatment in two 8-year-old patients, one with immature permanent molar diagnosed primarily with irreversible pulpitis and the other with partially vital maxillary central incisor. after access cavity preparation, partial pulpotomy in molar and full pulpotomy in central was performed, a...

abstract- the adverse effects of periodontal disease on dental pulp has been debated for many years. this case- control study was performed to assess the possible effects of advanced periodontal disease on the structure of dental pulp. fifty-two permanent teeth extracted because of advanced periodontitis with  5mm attachment loss and grade iii mobility were compared to fifty-two control teeth,...

this case report presents endodontic management of a mandibular lateral incisor with three canals using surgical dental operating microscope. this study describes the root canal variation of mandibular lateral incisor and highlights the importance of surgical operating microscope in detecting an unusual canal morphology.

www.endojournal.com.ar 540 Dental pulp is a highly vascularized and innervated tissue. The neural component of the pulp tissue consists of motor and sensory nerve fibers, the latter coming from the cranial nerve V; all stimuli that provoke these fibers will result in a painful sensation. Dental pulp tissue is not the only tissue with this characteristic. The eye cornea and the tympanic membrane...

BACKGROUND Dental pulp is used for PCR-based detection of DNA derived from host and bacteremic microorganims. Current protocols require odontology expertise for proper recovery of the dental pulp. Dental pulp specimen exposed to laboratory environment yields contaminants detected using universal 16S rDNA-based detection of bacteria. METHODOLOGY/PRINCIPAL FINDINGS We developed a new protocol b...

Stem cells are characterized by the ability to differentiate and to self-renew. Stem cells derived from human dental pulp have been shown to differentiate into osteoblasts serving as a potential source of autologous bone produced in vitro. The purpose of the present study was to isolate mesenchymal stem cells from dental pulp. Dental pulp was gently extracted from 27 intact human permanent thir...

AIM To evaluate catalase (CAT, EC 1.11.1.6) activity in healthy and inflamed dental pulp of young patient's teeth and to investigate if an active defense system oxidizing agents is present as a response to bacterial invasion. MATERIALS AND METHODS Twenty young patients between 15 and 25 ages, who were diagnosed to be healthy, were the source of the pulp tissue. The situation of the dental pul...

Traditional protocols involve the cleaning of the pulp chamber and root canals, the removal of bacteria and of the smear layer, and ultimately to the sealing of endodontic materials filling the pulp, and root lumen. Disinfection combined with mechanical enlargement allows occluding the lumen of the dental pulp with a central master cone, and lateral condensation using a series of small accessor...