We present a case of vitiligo associated with lipohypertrophy in a patient with type 1 diabetes on Lantus and Novorapid subcutaneous insulin. The patient, a 55-year-old woman, was diagnosed with type 1 diabetes 53 years ago. Following 11 years using Novorapid and Lantus she developed lipohypertrophy at her injection sites with associated depigmentation of the skin. The depigmentation has recurr...

Currently, there is an increase in the demand for aesthetics, which includes need a beautiful appearance. Gingival hyperpigmentation extremely disturbing aesthetic problem caused by melanin deposition of melanocytes basal and suprabasal layers epithelium. The color pigment can range from pale to dark brown or black, depending on amount distribution tissue. depigmentation therapy periodontal pla...

Recent publications have alerted clinicians to a syndrome of uveitic transilluminating iris depigmentation associated with systemic fluoroquinolones and other antibiotics. Bilateral acute iris transillumination, which is associated with loss of the iris pigment epithelium and results in iris transillumination, differs from the previously described bilateral acute depigmentation of the iris, whi...

The prevalence of skin depigmentation in the pretibial region is closely correlated in the adult Congolese population with conventional indices (microfilarial index, mean microfilarial density, cyst index) for the evaluation of endemic onchocerciasis. Individuals over 15 years of age in endemic villages who had a microfilarial index of 80-90%, had a cystic index of 60-70% and a pretibial depigm...

The chloroform extract of Ferula persica var. persica roots was found to inhibit red pigment production of Serratia marcescens. A bioguided fractionation study by preparative thin layer chromatography (PTLC) detected a fraction (Rf = 0.71, petroleum ether/EtOAc, 2:1 v/v), which was effective on depigmentation of Serratia marcescens. Using conventional spectroscopy methods, the active fraction w...

Bilateral acute depigmentation of the iris (BADI) is a new clinical entity of unknown etiology and is characterized by bilateral, symmetrical, and simultaneous depigmentation of the iris with focal or diffuse stromal atrophy; this condition generally has a good prognosis. We present a case of a 26-year-old woman who noted a spontaneous change in the iris color in both eyes in the last 2 months....