BACKGROUND Accurate detection and analysis of circulating tumor cells plays an important role in the diagnosis and treatment of metastatic cancer treatment. METHODS AND FINDINGS A cell microarray chip was used to detect spiked carcinoma cells among leukocytes. The chip, with 20,944 microchambers (105 µm width and 50 µm depth), was made from polystyrene; and the formation of monolayers of leuk...

In this paper we show that the move pruning method we presented at SoCS last year sometimes prunes all the least-cost paths from one state to another. We present two examples exhibiting this erroneous behaviour–a simple, artificial example and a slightly more complex example that arose in last year’s experiments. We then formally prove that a simple modification to our move pruning method makes...

Machining of AISI 304 austenitic stainless steel is considered to be difficult due its structural aspects and low thermal conductivity, which leads increased temperatures during machining. To overcome the challenges machining steel, several cooling lubricating techniques have been developed. The main objective this experimental study evaluate different turning conditions AISI304 under dry minim...

We present a design of balanced homodyne receivers suitable for ultra-low noise quantum applications such as continuous-variable key distribution and random number generation. For best bandwidth performance die-level low-parasitic photodiode together with low-noise high-speed transimpedance amplifier are explored planar lightwave circuit splitter chip serving photomixer. Bandwidths 750 MHz 2.6 ...

This paper presents a framework for high-level exploration, Register Transfer-Level (RTL) design and rapid prototyping of Network-on-Chip (NoC) architectures. From the high-level exploration, a selected NoC topology is derived, which is then implemented in RTL using an automated design flow. Furthermore, for verification purposes, appropriate self-checking testbenches for the verification of th...

This paper describes NoCBench, a benchmarking platform for evaluating the performance of Network-on-chip enabled Systems-on-chip. NoCBench includes an initial set of standardized processing cores, NoC components, and application benchmarks for system-level design exploration and analysis. It uses the NoCSim network on-chip simulator as the core simulation engine to execute these models and appl...

Chromatin immunoprecipitation followed by direct sequencing (ChIP-Seq) has revolutionalized the experiments in profiling DNA-protein interactions and chromatin remodeling patterns. However, limited statistical tools are available for modeling and analyzing the ChIP-Seq data thoroughly. We carefully study the data generating mechanism of ChIP-Seq data and propose a new model-based approach for d...

The generation of squeezed light in semiconductor materials opens opportunities for building on-chip devices that are operated at the quantum level. Here we study theoretically a source polariton dark solitons confined geometric potential well microcavities strong coupling regime. We show odd and even parities can be created by tuning depth. When driving depth linearly, bistability with two dif...

Abstract Progress is being made to deploy convolutional neural networks (CNNs) into the Internet of Things (IoT) edge devices for handling image analysis tasks locally. These require low-latency and low-power computation on low-resource IoT devices. However, CNN-based algorithms, e.g. YOLOv2, typically contain millions parameters. With increase in CNN’s depth, filters are increased by a power t...