background: developmental delay is one of the most common problems of children referred to pediatric neurology clinics. while there are reports on rehabilitation and its effects, limited studies are available to delineate pharmacotherapy of such children. because many children with developmental delay have abnormal findings in electroencephalography, we aimed to treat a group of these children,...

biotin is a water-soluble vitamin and co-factor for activation of carboxylases apoenzymes. biotinidase enzyme is essential for release of biotin from apoenzymes. absence of biotinidase is an autosomal recessive trait with a prevalence of 1 in 60000. clinical manifestations of biotinidase deficiency include dermatitis, alopecia, seizures, hypotonia, developmental delay, hearing loss, visual impa...

The purpose of this study was to estimate the prevalence of children aged 0-6 years with developmental delay (DD) and to examine age-period trends in the prevalence of DD diagnosis in Taiwan. For the study population, we selected children aged <6 years at baseline (in 1997-2002, N=2,308,790) from the National Health Insurance Research Database (a longitudinal database with annual medical record...

●●●. (J Dev Behav Pediatr 33:000 –000, 2012)

The present study investigated specific teacher factors that potentially influence teacher–child relationships with preschool-age children. One demographic questionnaire and three rating scales were used to survey 152 head teachers of 3–6-year-old children in community-based childcare and preschool centers in one midwestern state. There were 46 teachers who reported on their relationship with a...

Routines-based early intervention (RBEI) for children with or at risk for developmental delay encourages collaboration between professionals and families to enhance children's participation in family routines with family-selected goals. We conducted the first single-blinded randomized control trial to examine the effectiveness of a 6-month RBEI vs. traditional home visiting (THV), which uses a ...