The movements of cilia and flagella are driven by multiple species of dynein heavy chains (DHCs), which constitute inner- and outer-dynein arms. In Chlamydomonas, 11 DHC proteins have been identified in the axoneme, but 14 genes encoding axonemal DHCs are present in the genome. Here, we assigned each previously unassigned DHC gene to a particular DHC protein and found that DHC3, DHC4 and DHC11 ...

OBJECTIVES A preliminary study to investigate the orthodontic treatment need and its gender distribution in urban Iranian schoolchildren. STUDY DESIGN A cross-sectional study was carried out at the school premises. SUBJECTS AND METHODS For this survey, 502 subjects attending 6 different schools in the city of Isfahan, Iran (253 females and 249 males, aged 11-14 years) were randomly selected...

DHC-1, a herbal formulation, was tested for its anti-ulcer and antioxidant activity in rats. Effect of various doses (125, 250, 500, and 1000 mg/kg, p.o.) of DHC-1 was studied on gastric secretion and gastric ulcers in pylorus-ligation and on ethanol-induced gastric mucosal injury in rats. The reduction in ulcer index in both the models along with the reduction in volume and total acidity, and ...

Cellular lipids are speculated to act as key intermediates in Hedgehog signal transduction, but their precise identity and function remain enigmatic. In an effort to identify such lipids, we pursued a Hedgehog pathway inhibitory activity that is particularly abundant in flagellar lipids of Chlamydomonas reinhardtii, resulting in the purification and identification of ergosterol endoperoxide, a ...

The 19S outer arm dynein of trout sperm flagella is a complex of proteins composed of two heavy chains, five intermediate chains and at least six light chains. After dialysis against a low ionic strength buffer, its beta subunit was purified and used to generate a rabbit polyclonal antibody. This polyclonal antibody reacted strongly with the trout beta dynein heavy chain (DHC) but not with the ...

Two bio salt minerals, potassium sulphate, sodium sulphate and a mixture of both bio salts at the effective concentration of 1% which were added to the mulberry leaves of silkworm B. mori L., to evaluate their effect on the differential haemocyte counts (DHC) and absolute differential haemocyte counts (ADHC). Daily changes of five haemocyte types were investigated as, prohaemocytes, plasmatocyt...

Smith-Lemli-Opitz syndrome (SLOS) is an autosomal recessive disorder due to an inborn error of cholesterol metabolism, characterized by congenital malformations, dysmorphism of multiple organs, mental retardation and delayed neuropsychomotor development resulting from cholesterol biosynthesis deficiency. A defect in 3 -hydroxysteroid-delta7-reductase (delta7-sterol-reductase), responsible for t...

The present study assesses the validity and reproducibility of two occlusal indices for epidemiological studies--the Dental Aesthetic Index (DAI) and the Dental Health Component of the Index of Orthodontic Treatment Need (DHC-IOTN) for the identification of orthodontic treatment needs. The total of 131 study models was examined by an examiner (orthodontic specialist) for the determination of th...

statement of the problem malocclusion is a developmental problem, which results in social, psychological and functional problems for patients purpose the aim of this study was to evaluate the need for orthodontic treatment using the index of orthodontic treatment need (iotn) among the 11‒14-year-old students of hamadan schools in 2010 and to find the correlation between dental health component ...

OBJECTIVE Decompressive hemicraniectomy (DHC) for malignant middle cerebral artery (MCA) infarction has been shown to reduce mortality and improve functional outcomes in young adults; however, there is currently debate regarding how routinely such surgery should be performed in the clinical setting, considering the very high rate of disability and functional dependence among survivors. We herei...