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THIS STUDY AIMS TO COMPARE THE EFFICACY OF ANTISEPTIC DRESSINGS, HYPERBARIC OXYGEN THERAPY, AND RECOMBINANT HUMAN PLATELET DERIVED GROWTH FACTOR (RHPDGF) FOR TWO REASONS: i) to reduce the incidence of lower limb amputations in diabetic foot ulcer; ii) to limit the duration of stay in the hospital. A prospective randomized trial was conducted on 60 patients with stage III and IV diabetic foot ul...

Ulcerated diabetic foot is a complex problem. Ischaemia, neuropathy and infection are the three pathological components that lead to diabetic foot complications, and they frequently occur together as an aetiologic triad. Neuropathy and ischaemia are the initiating factors, most often together as neuroischaemia, whereas infection is mostly a consequence. The role of peripheral arterial disease i...

Diabetic foot ulcers are the consequence of multiple factors including peripheral neuropathy, decreased blood supply, high plantar pressures, etc., and pose a significant risk for morbidity, limb loss and mortality. The critical aspects of the wound healing mechanism and host physiological status in patients with diabetes necessitate the selection of an appropriate treatment strategy based on t...

Background: Foot ulcer is the most common complication that leads to amputation in diabetic patients. Purpose: To study the effect of intermittent pneumatic compression therapy (IPCT) in enhancing healing of chronic diabetic foot ulcer. Methods: Thirty-eight patients (13 men & 25 women) with type II diabetes and foot ulcer grade ІІ according to Wagner classification were recruited to participat...

BACKGROUND Foot ulcers (FU) are a significant complication of diabetes mellitus (DM) and a preceding factor leading to lower extremity amputation. The aim of this study was to evaluate the management of diabetic foot ulcer (DFU) in Babol, north of Iran. METHODS Five hundred twenty cases of diabetic foot ulcer that were hospitalized in two main teaching hospitals of Babol University of Medical...

Objective: The current study was conducted to compare the effect of 150,000 and 300,000 IU of vitamin D on the healing status of diabetic foot ulcer among the patients with diabetes. Materials and Methods: This randomized clinical trial was carried out on 47 patients with diabetic foot ulcer and vitamin deficiency during four weeks follow-up. The patients were randomly assigned into two groups...