the present study was aimed to evaluate the therapeutic potential of pimpinella tirupatiensis (pt) by assaying the activities of selective mitochondrial enzymes in streptozotocin induced diabetic rats. diabetic rats showed a significant (p < 0.01) reduction in the activities of oxidative enzymes succinate dehydrogenase (sdh), malate dehydrogenase (mdh), glutamate dehydrogenase (gdh) and isocitr...

background: it has been proposed that oxidative stress may contribute to the development of testicular abnormalities in diabetes. morus alba leaf extract (mae) has hypoglycemic and antioxidant properties. we, therefore, explored the impact of the administration of mae on steroidogenesis in diabetic rats. methods: to address this hypothesis, we measured the serum level of glucose, insulin, and f...

diabetes mellitus is a common endocrine disorder. anti-diabetic agents from natural and synthetic sources are available for the treatment of this disease. berberis integerrima is a medicinal shrub used in conventional therapy for a number of diseases. the aim of the present study was to investigate the effects of aqueous extract of berberis integerrima root (aebi) on some physiological paramete...

objective: diabetes is a metabolic disorder which impairs carbohydrate and lipid metabolism. it is accompanied by cognition impairment in diabetic patients and animal models. lipids play an important role in nerve membrane composition, structure and function. this study was designed to evaluate the effect of dietary butter and sesame oils on passive avoidance memory of streptozotocin (stz) diab...

background boswellia serrata has been used in a wide variety of diseases, including diabetes mellitus and inflammatory diseases. objectives this study focused on the effects of boswellia serrata aqueous extract on blood glucose and the complications of diabetes in the liver and kidneys and examined the impact of plant on reproduction in diabetic rats. materials and methods the antioxidant capac...

The in vivo anti-hyperglycemic effect of non-absorbable theaflavins, polyphenolic ingredients black tea, was evaluated spontaneously diabetic Torii (SDT) rats. A mixture theaflavins (25 mg/kg/day) administered to 8-week (wk)-old SDT rats for 20 weeks, showing improve the impaired glucose tolerance 22-wk old pre-diabetic both an oral test and a plasma insulin evaluation. At 28-wk presented with ...

angiotensin-converting enzyme (ace) inhibitors appear to correct many of the abnormalities associated with the vascular dysfunction found in diabetic patients. in this respect, quinapril is a unique ace inhibitor with multiple protective effects. the present study was carried out to investigate the effect of intraperitoneal administration of quinapril on the aortic reactivity of streptozotocin ...

conclusions our findings indicate that fenofibrate (ppar-α agonist) is able to prevent dn progression and improve kidney performance during chronic uncontrolled hyperglycemia possibly through increase in no bioavailability of kidney. results fenofibrate did not change the blood glucose of normal or diabetic rats. diabetes increased the proteinuria (82%) and blood creatinine of diabetic rats (4....

Aims: The present study aimed to evaluate anti-diabetic properties of AgNPs/chitosan/ascorbic acid nanocomposites (Ag-NCs) in streptozotocin-induced diabetic rats. Main methods: Eighteen male Wistar albino rats were divided into three main groups (6 rats/group); control, and Ag-NCs groups. Control group: after a single dose citrate buffer (0.1 mol/l, i.p), the orally received 1 ml distilled wat...

Objects: The phytochemical screening and the antihyperglycemic impact of Pelargonium gravelens were performed to judge ethanol extract using alloxan-induced diabetic rats. Methods: Intragastric ethanolic amount level 220 mg/kg body weight given alloxan-encouraged male albino rats for four weeks. Diabetic control assumed equivalent quantity vehicle (Dimethylsulfoxide, DMSO) processed together wi...