background: neonatal sepsis is a life-threatening disease with an incidence of 1 to 10 per 1000 live births and a mortality rate of 15% to 50%. the clinical signs are non-specific and indistinguishable from those caused by a variety of neonatal noninfectious disorders. objective: the aim of this study was to determine the importance of cd64 expression (fcgri), a neutrophil surface marker, in ea...

conclusions sepsis enhances the production of plasma ngal in critically ill neonates. thus plasma ngal can help clinicians diagnose sepsis in critically ill neonates during early phases. results the ngal levels were significantly higher in septic neonates compared with non-septic neonates (102.9 ± 69.9 ng/ml versus 29.2 ± 13.3 ng/ml, p value = 0.0001). an optimal cut off-point of 48 ng/ml for s...

neonatal sepsis is a disease of infants who are less than 1 month of age. these infants are clinically ill, and their blood culture are positive for bacteria. the reported incidence of neonatal sepsis for allinfants is 1 to 10 per 1000 live births. the mortality rate is 4.2-26%. the clinical signs are not specific and diagnosis of neonatal sepsis is one of the most difficult tasks in clinical m...

sepsis is a significant health problem with an estimated 750,000 new cases in the usa annually. it is also the third leading cause of death in developed countries, equaling the number of fatalities from acute myocardial infarction. the high sepsis-related mortalities mean there is an urgent need to improve the diagnosis and management of sepsis patients. the aim of this study was the evaluation...

background sepsis is one of the most important causes of morbidity and mortality in the intensive care units (icus). it is difficult to accurately differentiate sepsis from similar diseases rapidly. therefore, it becomes critical to identify any biomarker with the ability of differentiation between sepsis and nonsepsis conditions. the urokinase plasminogen activator receptor has been implicated...

Fast and appropriate therapy is the cornerstone in the therapy of sepsis. However, the discrimination of sepsis from non-infectious causes of inflammation may be difficult. Biomarkers have been suggested to aid physicians in this decision. There is currently no biochemical technique available which alone allows a rapid and reliable discrimination between sepsis and non-infectious inflammation. ...

background one of the main components involving in the pathogenesis and prognosis of sepsis and septic shock is natriuretic peptide. hemodynamic changes in sepsis or septic shock might explain increased plasma levels of these peptides circulations. objectives the present study aimed to assess the value of brain natriuretic peptide (bnp) in prediction of sepsis state and its related morbidity. w...