Rapid diagnostic tests are used for the determination of binary qualitative results not only uniquely in nonhospital-based but also in hospital-based tests. Principally, in developing countries, rapid diagnostic tests are the primary option since tests to be used in medical laboratories are discarded due to the higher cost. The test’s performance is evaluated to assure that the chance of result...

an increase of LV work performed in a few patients; in the remainder the left ventricle performed less work. In four dogs, selective left coronary arteriography resulting in increased ventricular filling pressure, was accompanied by an increase of left ventricular end-diastolic (VED) and stroke volumes; the ejection fraction and heart rate remained unchanged. If the animal studies (increased VE...

In this issue of Clinical Chemistry, Brown et al. (1 ) report a metaanalysis of studies of the test characteristics of the latex turbidimetric D-dimer test for the diagnosis of pulmonary embolism. In this editorial, we will discuss the importance of conducting systematic reviews of diagnostic evidence and their contribution to the practice of evidence-based laboratory medicine. Evidence-based p...

Purpose. recreational cross-country skiers can benefit from a performance diagnostic when planning a training program. The aim of this study was to establish a simple test protocol to measure endurance capacity and provide training recommendations. Methods. The relationship between endurance performance and cross-country skiing technique was assessed using two tests. First, a lactate threshold ...

Recently, the argument has been made that receiver operating characteristic (ROC) analysis should be used to compare the diagnostic performance of different lineup procedures. However, a drawback to ROC analysis is that is requires multiple correct and false ID rates for each lineup procedure being compared. When only a single pair of correct and false ID rates is measured, what dependent measu...