Abstract Chronic kidney disease (CKD) is characterized by clustered age-independent concentric LV geometry, geometry-independent systolic dysfunction, and age heart rate-independent diastolic dysfunction. Concentric geometry always associated with echocardiographic markers of abnormal relaxation increased myocardial stiffness, two hallmarks Non hemodynamic mechanisms such as metabolic electroly...

background: diabetes mellitus is capable of impairing the myocardial function. several studies have documented the influential impact of diabetes mellitus on the left ventricular function. the right ventricular function plays a significant role in the overall myocardial contractility; hence, this study was undertaken to evaluate the effect of diabetes mellitus type ii on the right ventricular f...

coronary artery disease is one of the most common causes of mortality and morbidity across the world. its treatment includes medical treatment, coronary artery bypass graft (cabg) and percutaneous coronary intervention (pci). the purpose of this study was to investigate the effect of pci on echocardiographic findings of left ventricular (lv) systolic and diastolic function. 115 patients with co...

Myotonic dystrophy type 1 (MD) is the most common autosomal dominant muscular dystrophy in adults. Cardiac involvement is mainly characterized by conduction abnormalities and arrhythmias. We sought to assess diastolic function in MD patients. Echocardiography-Doppler was performed in Steinert's patients and in a control group completed by tissue Doppler imaging (TDI). Twenty-six patients with S...

Although both dopamine and dobutamine are potent positive inotropic agents, multiple studies indicate that dopamine may produce a rise in left ventricular (LV) filling pressure, while dobutamine often has the opposite effect. To ascertain the pharmacological and hemodynamic mechanisms responsible for the elevation in LV filling pressure observed with dopamine, we administered incremental infusi...

Heart failure has reached epidemic proportions, and diastolic heart failure or heart failure with preserved ejection fraction (HFpEF) constitutes about 50% of all heart failure admissions. Long-term prognosis of both reduced ejection fraction heart failure and HFpEF are similarly dismal. No pharmacologic agent has been developed that actually treats or repairs the physiologic deficit(s) respons...